Encountering Dapsone Poisoning In a Child at the Emergency Department of a Tertiary Care Hospital in Eastern Nepal

Authors

  • Gyanendra Malla Department of General Practice and Emergency Medicine B. P. Koirala Institute of Health Sciences, Dharan,
  • B Gauchan Department of General Practice and Emergency Medicine, B. P. Koirala Institute of Health Sciences, Dharan
  • S Chaudhary Department of Paediatrics and Adolescent Health B. P. Koirala Institute of Health Sciences, Dharan
  • R Bhandari Department of General Practice and Emergency Medicine, B. P. Koirala Institute of Health Sciences, Dharan
  • P P Gupta Department of General Practice and Emergency Medicine, B. P. Koirala Institute of Health Sciences, Dharan

DOI:

https://doi.org/10.3126/hren.v12i1.11988

Keywords:

Dapsone, Leprosy, Poisoning

Abstract

Dapsone (4, 4’-diaminophenylsulfone), a sulfonamide derivative, was introduced in 1943 as an effective chemotherapeutic agent for leprosy and still is an important drug for the treatment of this disease. Because of its use in various conditions, its toxicity is commonly seen in adults but rare in children. Rapid clinical assessment, measurement of methemoglobin and institution of methylene blue where indicated decreases the morbidity and mortality of dapsone poisoning. We report a case of 2 year old female with accidental ingestion of 20 tablets (20gm) of dapsone.

DOI: http://dx.doi.org/10.3126/hren.v12i1.11988

Health Renaissance 2014;12(1):52-54

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Author Biography

Gyanendra Malla, Department of General Practice and Emergency Medicine B. P. Koirala Institute of Health Sciences, Dharan,

Professor & HOD

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Published

2015-01-28

How to Cite

Malla, G., Gauchan, B., Chaudhary, S., Bhandari, R., & Gupta, P. P. (2015). Encountering Dapsone Poisoning In a Child at the Emergency Department of a Tertiary Care Hospital in Eastern Nepal. Health Renaissance, 12(1), 52–54. https://doi.org/10.3126/hren.v12i1.11988

Issue

Section

Case Reports