Effect of Carbafuran Pesticide on Mitotic Chromosomes of Mus musculus

  • Manisha Kumari Post Graduate Department of Biotechnology, T.M. Bhagalpur University, Bhagalpur-812007
  • Rohit Kumar Verma Post Graduate Department of Biotechnology, T.M. Bhagalpur University, Bhagalpur-812007
  • Prabhat Kumar Roy University Department of Zoology, T . M. Bhagalpur University, Bhagalpur-812007
Keywords: Carbafuran, genotoxic, bone marrow cells, Swiss albino mice

Abstract

The Genotoxic effect of the carbafuran pesticide was evaluated in the metaphasic chromosomes of bone marrow cells of female Swiss albino mice, Mus musculus . Six week old mice were put into different groups(six mice per group) and treatment were done according to experimental plan (CLD15 i.e. lower dose =30ppm or 0.03mg/ml and CHD30 i.e. higher dose =300ppm or 0.3mg/ml).The test material was administered orally for 15 days in CLD15 and for 30 days in CHD30 test groups of female mice. The result revealed that the frequency of chromosomal abnormalities i.e. structural and numerical changes were11.5% in control, 74.0%in CLD15 and 99.0%in CHD30, respectively in bone marrow cells of female mice.

Int. J. Appl. Sci. Biotechnol. Vol 6(2): 169-173

 

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Abstract
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PDF
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Published
2018-06-29
How to Cite
Kumari, M., Verma, R. K., & Roy, P. K. (2018). Effect of Carbafuran Pesticide on Mitotic Chromosomes of Mus musculus. International Journal of Applied Sciences and Biotechnology, 6(2), 169-173. https://doi.org/10.3126/ijasbt.v6i2.20434
Section
Research Articles