Bangladeshi Wild Date Palm Fruits (Phoenix sylvestris): Promising Source of Anti-cancer Agents for Hepatocellular Carcinoma Treatment

  • Farhana Shikder Lamia Department of Genetic Engineering and Biotechnology, East West University, Aftab Nagar, Dhaka-1212, Bangladesh
  • Roushney Fatima Mukti Department of Genetic Engineering and Biotechnology, East West University, Aftab Nagar, Dhaka-1212, Bangladesh https://orcid.org/0000-0001-7059-8165
Keywords: Anticancer agent, ; hepatocellular carcinoma, Phoenix sylvestris

Abstract

Many natural products such as fruits and vegetables are promising amends as safe, effective and affordable approaches to control cancer development and progression, since they are inexpensive and available without any hazards. For instance, the aqueous extract of Ajwa dates (Phoenix dactilyfera) has been found to improve liver function through the restoration of anti-oxidant enzymes, liver enzymes, and cytokines balance and gene expression to normal levels. As the treatment and prognosis of Hepatocellular carcinoma, one of the leading causes of cancer associated deaths globally, has been found to be better if the liver function of the patient can be preserved, Ajwa date extract has been used together with the conventional therapeutics for the treatment of this disease. However, no study has been conducted so far on the anticancer activity of Bangladeshi wild date palm fruits (Phoenix sylvestris) despite the fact that it contains apigenin, quercetin, glucans, luteolin, and iron and vitamin complex. Therefore, in this review we discussed an idea that potential anticancer agents can be isolated from the extract of these fruits, which can eventually be used as an indigenous substance for the treatment of Hepatocellular carcinoma in our country and also the liver cancer inhibitory effects of the aqueous extract of these dates can be evaluated in rat model.

Int. J. Appl. Sci. Biotechnol. Vol 9(1): 32-37

 

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Abstract
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Published
2021-03-30
How to Cite
Lamia, F. S., & Mukti, R. F. (2021). Bangladeshi Wild Date Palm Fruits (Phoenix sylvestris): Promising Source of Anti-cancer Agents for Hepatocellular Carcinoma Treatment. International Journal of Applied Sciences and Biotechnology, 9(1), 32-37. https://doi.org/10.3126/ijasbt.v9i1.36110
Section
Mini Reviews