Study of hypovitaminosis D as a cause of chronic widespread pain in patients presenting to rheumatology clinic

Authors

  • Binit Vaidya Alka Hospital, Jawalakhel, Kathmandu
  • Shweta Nakarmi Alka Hospital, Jawalakhel, Kathmandu
  • Arvind Chaudhary Alka Hospital, Jawalakhel, Kathmandu
  • Poojan Batajoo Nepal Medical College, Kathmandu
  • Nija Rajbhandari Nepal Medical College, Kathmandu

DOI:

https://doi.org/10.3126/jaim.v3i1.10694

Keywords:

Chronic pain, fibromyalgia, vitamin D deficiency

Abstract

Background and aims: Hypovitaminosis D is common in south-east Asian countries. Deficient vitamin-D level is likely to be associated with chronic muscular pains. We do not have data from our country regarding the magnitude of this problem.

Methods: A prospective open labeled study at rheumatology opd from December 2009 to December 2012. Patients with chronic widespread pain and bone pains of >3 months duration were included in the study. Hypothyroidism, chronic renal failure and other rheumatological diagnosis except fibromyalgia were excluded. Visual analogue score (VAS) for pain and serum Vitamin-D levels were measured. Patients with low Vitamin-D were given oral Vitamin-D 60,000IU for 6 months. Response to therapy was evaluated using improvement in VAS.

Results: Among 1680 patients, 66?2% were females. Hypovitaminosis-D was seen in 1388(82?6%), of which 27?5% had severe deficiency with Vitamin D levels <10ng/ml. Fibromyalgia overlap present in 25?7%. Mean initial VAS score was 8?7, 8?2 and 7?4 for patients in severe deficiency, mild deficiency and insufficiency group respectively. At 6 months follow-up, the VAS scores were 0, 2?1 and 3?6 respectively. After 6 months of treatment, no improvement was seen in 196 patients (11?6%) and all non-responders had fibromyalgia overlap. Vitamin- D level was checked again in non-responders and repeat vitamin-D levels were still low in 10 of them.

Conclusions: Hypovitaminosis-D can be a significant cause of Chronic widespread pain in the general population and seems to aggravate the pain of fibromyalgia. Improvement was rapid and better in severe cases.

DOI: http://dx.doi.org/10.3126/jaim.v3i1.10694

Journal of Advances in Internal Medicine 2014;03(01):1-4

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Published

2014-07-03

How to Cite

Vaidya, B., Nakarmi, S., Chaudhary, A., Batajoo, P., & Rajbhandari, N. (2014). Study of hypovitaminosis D as a cause of chronic widespread pain in patients presenting to rheumatology clinic. Journal of Advances in Internal Medicine, 3(1), 1–4. https://doi.org/10.3126/jaim.v3i1.10694

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Section

Original Articles