Hypokalemic quadriparesis due to renal tubular acidosis in a patient with Sjögren’s syndrome: A case series

  • Abhishek Maskey Department of Nephrology, Nepal Medical College and Teaching Hospital, Kathmandu
  • Neeraj Singh Department of Nephrology, Nepal Medical College and Teaching Hospital, Kathmandu
  • Santosh Gautam Department of Internal Medicine, Nepal Medical College and Teaching Hospital, Kathmandu
  • Prashant Bhattarai Department of Nephrology, Nepal Medical College and Teaching Hospital, Kathmandu
  • Prakash Poudyal Department of Nephrology, Nepal Medical College and Teaching Hospital, Kathmandu
  • Dhiraj Narayan Manandhar Department of Nephrology, Nepal Medical College and Teaching Hospital, Kathmandu
  • Pramod Kumar Chhetri Department of Nephrology, Nepal Medical College and Teaching Hospital, Kathmandu
Keywords: Hypokalemia, quadriparesis, renal tubular acidosis type I, Sjögren’s syndrome

Abstract

We report two cases of female patients presented with hypokalemia secondary to renal tubular acidosis. Sjögren’s syndrome was diagnosed in both the patients on the basis of histopathological and autoantibodies tests. The patients were treated with potassium and bicarbonate supplementation. Renal involvement in Sjögren’s syndrome is not uncommon and may precede sicca complaints. The pathology in most cases is a tubulointerstitial nephritis causing distal renal tubular acidosis and rarely, hypokalemic paralysis. The complications of renal tubular acidosis include life threatening hypokalemia, nephrolithiasis, chronic renal failure, growth retardation and osteomalacia. These consequences can be avoided if the diagnosis is made early and lifelong potassium and alkali supplementation is initiated. Primary Sjögren’s syndrome should be considered in women with acute weakness and hypokalemia.

DOI: http://dx.doi.org/10.3126/jaim.v3i1.10701

Journal of Advances in Internal Medicine 2014;03(01):30-33

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Abstract
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PDF
473
Published
2014-07-03
How to Cite
Maskey, A., Singh, N., Gautam, S., Bhattarai, P., Poudyal, P., Manandhar, D., & Chhetri, P. (2014). Hypokalemic quadriparesis due to renal tubular acidosis in a patient with Sjögren’s syndrome: A case series. Journal of Advances in Internal Medicine, 3(1), 30-33. https://doi.org/10.3126/jaim.v3i1.10701
Section
Case Reports