Cytomegalovirus: A possible cause of Persistent Refractory Immune Thrombocytopenic Purpura

  • Raksha Shrestha Department of Hematology-Oncology, College of Medicine, University of Illinois at Chicago
  • Damiano Rondelli Department of Hematology-Oncology, College of Medicine, University of Illinois at Chicago
  • Mingma Thsering Sherpa Department of Hematology-Oncology, College of Medicine, University of Illinois at Chicago
Keywords: Cytomegalovirus, Immune Thrombocytopenic Purpura

Abstract

We present a case of a healthy 22 years old who presented with bruising and hematoma following a minor trauma. Investigations showed severe thrombocytopenia but complete hematological investigations did not reveal a cause. An aggressive treatment with steroids, IVIG, anti-D, splenectomy and immunosuppressant proved to be refractory. A subclinical transaminitis prompted an infectious workup which revealed Cytomegalovirus infection. Platelet count improved and remained stable after eradication of Cytomegalovirus. We conclude that infection with CMV should be ruled out in cases of severe refractory immune thrombocytopenic purpura.

DOI: http://dx.doi.org/10.3126/jaim.v3i1.10704  

Journal of Advances in Internal Medicine 2014;03(01):42-45

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Published
2014-07-03
How to Cite
Shrestha, R., Rondelli, D., & Sherpa, M. (2014). Cytomegalovirus: A possible cause of Persistent Refractory Immune Thrombocytopenic Purpura. Journal of Advances in Internal Medicine, 3(1), 42-45. https://doi.org/10.3126/jaim.v3i1.10704
Section
Case Reports