Small Volume Plasma Exchange as an Alternative to Conventional Plasma Exchange and Intravenous Immunoglobulin for Myasthenic Crisis: A Case Report

Authors

  • Ankit Rimal Department of Critical Care Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal
  • Gentle Sunder Shrestha Department of Critical Care Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal
  • Bishwas Pradhan Department of Cardiothoracic and Vascular Anaesthesiology, Manmohan Cardiothoracic, Vascular and Transplant Centre, Tribhuvan University Teaching Hospital, Kathmandu, Nepal
  • Subhash Prasad Acharya Department of Critical Care Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal

DOI:

https://doi.org/10.3126/jaim.v11i2.52407

Keywords:

Intravenous immunoglobulin, Myasthenic crisis, Plasma exchange, Small volume plasma exchange

Abstract

Myasthenic crisis is a life-threatening condition. At times it manifests as the initial presentation of the underlying myasthenia gravis. Rapidly acting therapies for treatment of this condition are plasma exchange and intravenous immunoglobulin. We report a case of myasthenic crisis in a young female, presenting with respiratory failure and bulbar symptoms. She had significantly raised titres of anti-acetylcholine receptor antibody. She was treated with multiple sessions of small volume plasma exchange. This modification of conventional plasma exchange significantly reduces costs and is potentially an effective alternative to conventional plasma exchange and intravenous immunoglobulin in resource-poor settings.

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Published

2023-02-12

How to Cite

Rimal, A. ., Shrestha, G. S. ., Pradhan, B. ., & Acharya, S. P. . (2023). Small Volume Plasma Exchange as an Alternative to Conventional Plasma Exchange and Intravenous Immunoglobulin for Myasthenic Crisis: A Case Report. Journal of Advances in Internal Medicine, 11(2), 52–54. https://doi.org/10.3126/jaim.v11i2.52407

Issue

Section

Case Reports