Histamine in Foods: Its Safety and Human Health Implications

  • Krishna Prasad Rai Department of Food Technology and Quality Control, Babarmahal
  • Hare Ram Pradhan Department of Food Technology and Quality Control, Babarmahal
  • Bal Kumari Sharma Department of Food Technology and Quality Control, Babarmahal
  • Som Kant Rijal Department of Food Technology and Quality Control, Babarmahal
Keywords: Histamine, fish, scombrotoxin, Nepalese perspective, safety

Abstract

This article reviews the overall aspects of histamine, one of the most potent biogenic amine, which is formed by decarboxylation of histidine protein rich foods in fish and fish products, dairy products, meat and meat products, fermented vegetables and soy products, and alcoholic beverages such as wine and beer. Normally, three basic conditions i.e. high content of free histidine, bacterial histidine decarboxylase activity and high temperature storage environment elevates the level of histamine in foods. Several chromatographic methods utilizing thin layer chromatography (TLC), high performance liquid chromatography (HPLC), gas chromatography (GC) and colorimetry, fluorimetry and ELISA technique have been developed for the analysis of biogenic amine including histamine. Histamine usually exceeding 1000 mg/kg has been implicated with scombrotoxicosis. Several government authorities including Codex Alimentarious Commission has also set the level of histamine in different food products varying from 5 to 40 mg/100g. Proper technical regulations and surveillance mechanism as well as hygienic and bio-technological advancement in food manufacturing establishment could be the good preventive measures of low histamine foods in future. 

DOI: http://dx.doi.org/10.3126/jfstn.v8i0.11720

J. Food Sci. Technol. Nepal, Vol. 8 (1-11), 2013

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Abstract
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PDF
3499
Published
2014-12-15
How to Cite
Rai, K., Pradhan, H., Sharma, B., & Rijal, S. (2014). Histamine in Foods: Its Safety and Human Health Implications. Journal of Food Science and Technology Nepal, 8, 1-11. https://doi.org/10.3126/jfstn.v8i0.11720
Section
Review Articles