Phytochemical Screening, Pharmacognostic Evaluation and Biological Activity of Amaranthus spinosus L

Authors

  • Dharma Prasad Khanal Manmohan Memorial Institute of Health Sciences, Nakhhu, Lalitpur
  • B Raut Manmohan Memorial Institute of Health Sciences, Nakhhu, Lalitpur
  • K S Dangol National Model College for Advanced Learning, Khushibu, Kathmandu

DOI:

https://doi.org/10.3126/jmmihs.v1i4.11999

Keywords:

Antimicrobial activity, Brine shrimp lethality phytochemical analysis, Vascular bundle

Abstract

Herbal medicines possess a great demand in both developed and developing countries as a source of primary health care owing to their attributes having wide biological and medicinal activities, high safety margins and lesser costs. People living in rural areas of Nepal depend largely in the herbal medicines for the treatment. The present study concerns with the study of pharmacognostic characteristics, phytochemical constituents and the biological activity of Amaranthus spinosus L. The hexane, chloroform, ethanolic and aqueous extract of its aerial parts were subjected to preliminary phytochemical analysis and detected saponin, carbohydrate, tannin, protein, glycoside, flavonoid and phenol as phytoconstituents. The transverse section of the stem and leaves showed characteristic vascular bundle tissues. All the extracts were used for testing the antimicrobial activity and brine shrimp lethality. No extract showed the antimicrobial activity and ethanolic extract showed LC50 value of 31.62 ppm. Hexane, chloroform and water extracts were less toxic with LC50 values 236.88 ppm,194.98 ppm and 320.71 ppm respectively.

DOI: http://dx.doi.org/10.3126/jmmihs.v1i4.11999

Journal of Manmohan Memorial Institute of Health Sciences

Vol. 1, Issue 4, 2015

Page: 29-34

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Published

2015-02-01

How to Cite

Khanal, D. P., Raut, B., & Dangol, K. S. (2015). Phytochemical Screening, Pharmacognostic Evaluation and Biological Activity of Amaranthus spinosus L. Journal of Manmohan Memorial Institute of Health Sciences, 1(4), 29–34. https://doi.org/10.3126/jmmihs.v1i4.11999

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