Phytochemical Investigation and Antibacterial Activity of Bergenia ligulata

Authors

  • M. Rajbhandari Research Center for Applied Science and Technology, Tribhuvan University, Kathmandu
  • H. R. Khatri Central Department of Chemistry, Tribhuvan University, Kathmandu
  • M. Lalk Institute of Pharmacy, Department of Pharmaceutical Biology, University of Greifswald, D-17487
  • M. B. Gewali Central Department of Chemistry, Tribhuvan University, Kathmandu
  • U. Lindequist Institute of Pharmacy, Department of Pharmaceutical Biology, University of Greifswald, D-17487

Keywords:

Bergenia ligulata, Antibacterial, Bergenin, 11-O-p-hydroxybenzoylbergenin, 6-O-galloylarbutin, Epiafzelechin

Abstract

In the course of screening of plant extracts for antimicrobial activity, the methanolic extract of Bergenia ligulata (Saxifragaceae) exhibited antibacterial activity against gram-positive bacteria. Fractionation of ethylacetate soluble phase of the methanol extract led to the isolation of bergenin (1), 11-O-p-hydroxybenzoylbergenin (2), 6-O-galloylarbutin (3) and epiafzelechin (4). Except bergenin, other compounds were isolated for the first time from B. ligulata.

DOI: http://dx.doi.org/10.3126/jncs.v28i0.8118

Journal of Nepal Chemical Society
Vol. 28, 2011
Page: 110-114
Uploaded Date: May 24, 2013

Abstract
1206

Published

2013-05-24

How to Cite

Phytochemical Investigation and Antibacterial Activity of Bergenia ligulata. (2013). Journal of Nepal Chemical Society, 28, 110-114. https://doi.org/10.3126/jncs.v28i0.8118

Issue

Vol. 28 (2011)

Section

Articles

License

© Journal of Nepal Chemical Society

How to Cite

Phytochemical Investigation and Antibacterial Activity of Bergenia ligulata. (2013). Journal of Nepal Chemical Society, 28, 110-114. https://doi.org/10.3126/jncs.v28i0.8118