Synthesis and Antimicrobial Activity of Azepine Analogue of Lignan

Authors

  • Ashok Kumar Singh Department of Chemistry, Tri-Chandra Multiple Campus, Tribhuvan University

DOI:

https://doi.org/10.3126/jncs.v29i0.9236

Keywords:

Diphenylamine, Azepine, Podophyllotoxin,

Abstract

Diphenylamine (1) was condensed with maleic anhydride (2) in the presence of sodium hydride and dry benzene, 4-N,N-diphenyl amine-4-oxo-2-butenoic acid (3) was achieved. Intramolecular cyclization of compound 3 with PPE afforded 1-phenyl-1H-benzo[b] azepine-2,5 dione (4). 

DOI: http://dx.doi.org/10.3126/jncs.v29i0.9236

Journal of Nepal Chemical Society

Vol. 29, 2012

Page: 44-47

Uploaded date : 12/3/2013

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Published

2013-12-03

How to Cite

Singh, A. K. (2013). Synthesis and Antimicrobial Activity of Azepine Analogue of Lignan. Journal of Nepal Chemical Society, 29, 44–47. https://doi.org/10.3126/jncs.v29i0.9236

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