Synthesis of Triazole derivative: [4-(benzylideneamino)-5-phenyl -4H-1,2,4 – triazole-3-thiol]
The basic nucleus 4-(amino)-5-phenyl-l-4H-1,2,4-triazole-3-thiol has been synthesized by cyclisation of potassium dithiocarbazinate with hydrazine hydrate using water as solvent under reflux condition for 3-4 h. The compound which has been synthesized successfully was subjected to condensation with benzaldehyde to synthesize 4-(benzylideneamino)-5-phenyl -4H-1,2,4 – triazole-3-thiol (Schiff base). The compounds were confirmed by physical parameters (melting point), chromatographic methods (TLC) and spectroscopic methods (IR and NMR).
Journal of Nepal Chemical Society
Vol. 30, 2012
Uploaded date: 12/20/2013