Phenytoin Induced Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)

  • NK Natt Senior Resident, Department of Pharmacology, Government Medical College, Amritsar
  • S Tarsem Assistant professor, Department of Paediatrics, SGRD Institute of Medical Sciences and Research, Vallah
  • Dr Anuba Junior Resident, Department of Paediatrics, SGRD Vallah, Amritsar
  • S Simarjeet Junior Resident, Department of Paediatrics SGRD Vallah, Amritsar
  • M Sharma Junior Resident, Department of Paediatrics SGRD Vallah, Amritsa
  • S Harmanjit Senior Resident, Department of Pharmacology, All India Institute of Medical Sciences, Delhi
Keywords: Adverse effect, Skin rash, Visceral involvement

Abstract

Drug reaction with eosinophilia and systemic symptoms (DRESS) is a rare and potentially fatal adverse effect characterized by a skin rash with visceral involvement and haematological abnormalities. This adverse drug effect is often misdiagnosed and under-reported especially in paediatric age group due to its rarity and high occurrence of skin rash in various other viral illnesses of children. We report a case of DRESS in a three months old male child. A high index of suspicion, rapid diagnosis and prompt withdrawal can be life-saving for the patient.

J Nepal Paediatr Soc 2015;35(1):73-75

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Abstract
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PDF
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Published
2015-10-08
How to Cite
Natt, N., Tarsem, S., Anuba, D., Simarjeet, S., Sharma, M., & Harmanjit, S. (2015). Phenytoin Induced Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS). Journal of Nepal Paediatric Society, 35(1), 73-75. https://doi.org/10.3126/jnps.v35i1.10539
Section
Brief Reports/Case Reports/Case Series