Methotrexate as a Suspected Trigger of Macrophage Activation Syndrome in Juvenile Idiopathic Arthritis

  • Soumya Roy Institute Of Child Health, Kolkata
  • Subroto Chakrabartty Institute Of Child Health, Kolkata
Keywords: Macrophage activation syndrome, Methotrexate, Systemic Onset Juvenile Idiopathic Arthritis

Abstract

A four year old girl with systemic onset juvenile idiopathic arthritis (SOJIA) developed macrophage activation syndrome (MAS) shortly after starting methotrexate. We observed methotrexate is a likely trigger of MAS in SOJIA. Possibly, there are only two case reports suggesting methotrexate triggered MAS. We reviewed the literature for possible mechanisms.

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Author Biographies

Soumya Roy, Institute Of Child Health, Kolkata

Post graduate trainee and junior resident,, Dept Of PaediatricsĀ 

Subroto Chakrabartty, Institute Of Child Health, Kolkata
Professor Of Paediatrics
Published
2017-10-04
How to Cite
Roy, S., & Chakrabartty, S. (2017). Methotrexate as a Suspected Trigger of Macrophage Activation Syndrome in Juvenile Idiopathic Arthritis. Journal of Nepal Paediatric Society, 37(1), 95-97. https://doi.org/10.3126/jnps.v37i1.16894
Section
Case Reports