Recurrent Pneumonias and Bronchiectasis - Is it an Immunodeficiency Disorder? - A Case Report

  • Sumit Agrawal Department of Paediatrics, Kanti Children’s Hospital, Maharajgunj, Kathmandu, Nepal 
  • S Shreeram Department of Paediatrics, Kanti Children’s Hospital, Maharajgunj, Kathmandu, Nepal 
  • A Jha Department of Paediatrics, Kanti Children’s Hospital, Maharajgunj, Kathmandu, Nepal 
  • B Prajapati Department of Paediatrics, Kanti Children’s Hospital, Maharajgunj, Kathmandu, Nepal 
Keywords: Common variable immunodeficiency, cytopenias, fungal pneumonia, recurrent pneumonia

Abstract

Common Variable Immunodeficiency (CVID) is a form of primary immunodeficiency disorder characterised by hypogammaglobulinemia and recurrent sino-pulmonary infections. Its diagnosis is based on the presence of low serum IgG (< 2 SD below normal for age) with or without low IgA/ IgM levels and presentation beyond two years of age. These children also have disorders of autoimmunity with majority of them presenting as autoimmune cytopenias, predominantly thrombocytopenia and some having anaemia and neutropenias. Here we report a nine years old boy with past history of recurrent pneumonia, presenting this episode with fungal pneumonia, thrombocytopenia and anaemia eventually diagnosed as CVID.

Downloads

Download data is not yet available.
Abstract
53
PDF
49
Published
2020-09-11
How to Cite
Agrawal, S., Shreeram, S., Jha, A., & Prajapati, B. (2020). Recurrent Pneumonias and Bronchiectasis - Is it an Immunodeficiency Disorder? - A Case Report. Journal of Nepal Paediatric Society, 40(2), 139-142. https://doi.org/10.3126/jnps.v40i2.29625
Section
Case Reports