Incidence and Risk Factors Association for Ventilator Associated Pneumonia in Neontal Intensive Care Unit

Authors

  • Naresh Kumar Department of Paediatrics, Sri Guru Ram Das Institute of Medical Sciences and Research, Mehta Road, Post Office Vallah, Amritsar, Punjab – 143501, India.
  • Preeti Malhotra Department of Paediatrics, Sri Guru Ram Das Institute of Medical Sciences and Research, Mehta Road, Post Office Vallah, Amritsar, Punjab – 143501, India.
  • Amanjeet Kaur Bagga Department of Paediatrics, Sri Guru Ram Das Institute of Medical Sciences and Research, Mehta Road, Post Office Vallah, Amritsar, Punjab – 143501, India.
  • Gagandeep Kaur Department of Paediatrics, Sri Guru Ram Das Institute of Medical Sciences and Research, Mehta Road, Post Office Vallah, Amritsar, Punjab – 143501, India.

DOI:

https://doi.org/10.3126/jnps.v42i1.38603

Keywords:

Mechanical ventilation, neonatal intensive care unit, reintubation, ventilator associated pneumonia

Abstract

Introduction: Ventilator Associated Pneumonia (VAP), the nosocomial pneumonia developing in mechanically ventilated patients after 48 hours of mechanical ventilation, is the second commonest nosocomial infection in the neonatal intensive care unit (NICU). VAP occurring within 96 hours of initiation of mechanical ventilation is termed as early VAP and later than that is known as late VAP. The aim of this study was to determine the incidence rate and risk factors of early and late ventilator associated pneumonia in NICU.

Methods: The study was conducted from December 2015 to November 2017 in which 40 neonates were ventilated for more than 48 hours of which those who developed VAP as per CDC criteria were enrolled in the study. Birth weight, gestation age, reintubation if needed and number of days of ventilation were noted. Statistical associations were further evaluated between various parameters of VAP and time of development of VAP.

Results: Incidence of Early VAP was 12.5% and that of Late VAP was 87.5%. 93.95% neonates who were reintubated developed VAP. Duration of mechanical ventilation and re-intubation were significantly associated with the time of development of VAP. Birth weight and gestation age were statistically insignificant factors in determining VAP.

Conclusions: Re-intubation and duration of mechanical ventilation are a significant risk factor for development of late VAP. Gestation age and birth weight have been identified as additional risk factors. Early diagnosis is necessary for appropriate treatment and decreased hospital stay.

Downloads

Download data is not yet available.
Abstract
72
PDF
79

Downloads

Published

2022-11-27

How to Cite

Kumar, N. ., Malhotra, P. ., Kaur Bagga, A. ., & Kaur, G. . (2022). Incidence and Risk Factors Association for Ventilator Associated Pneumonia in Neontal Intensive Care Unit. Journal of Nepal Paediatric Society, 42(1), 69–73. https://doi.org/10.3126/jnps.v42i1.38603

Issue

Vol. 42 No. 1 (2022)

Section

Original Articles

License

Copyright (c) 2022 Dr Naresh Sharma, Preeti Malhotra Kaur, Amanjeet Kaur Bagga, Gagandeep Kaur

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors who publish with this journal agree to the following terms:

Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).