Acetaminophen induced Stevens Johnson syndrome - Toxic Epidermal Necrolysis Overlap Syndrome: A rare Adverse Reaction

Authors

  • Saiprasad Onkareshwar Kavthekar Department of Paediatrics, D.Y. Patil Medical College, D. Y. Patil Education Society (Deemed to be University), Kolhapur- 416003, Maharashtra, India
  • K. Amith Department of Paediatrics, D.Y. Patil Medical College, D. Y. Patil Education Society (Deemed to be University), Kolhapur- 416003, Maharashtra, India
  • Anil Bapurao Kurane Department of Paediatrics, D.Y. Patil Medical College, D. Y. Patil Education Society (Deemed to be University), Kolhapur- 416003, Maharashtra, India.
  • Yoganand J Phulari Department of Dermatology, D.Y. Patil Medical College, D. Y. Patil Education Society (Deemed to be University), Kolhapur- 416003, Maharashtra, India.

DOI:

https://doi.org/10.3126/jnps.v42i1.39225

Keywords:

acetaminophen, Child, Toxic Epidermal Necrolysis, , Steven-Johnson Syndrome

Abstract

Stevens Johnson syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are hyper sensitive life - threatening rare dermatological reactions. In SJS - TEN overlap syndrome, the extent and severity of epidermal detachment is 10- 30%. Drugs like sulfonamides, nonsteroidal anti- inflammatory agents, antibiotics and anticonvulsants are the commonest precipitants. Here, we present a rare case of SJS - TEN overlap syndrome in a previously normal 11 years old girl after acetaminophen intake for fever. This case report is intended to make paediatricians aware that the adverse reaction like SJS - TEN overlap syndrome can develop with a drug like acetaminophen which is supposed to be the safest antipyretic in paediatrics.

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Published

2022-11-27

How to Cite

Kavthekar, S. O., Amith, K., Bapurao Kurane, A. ., & J Phulari, Y. (2022). Acetaminophen induced Stevens Johnson syndrome - Toxic Epidermal Necrolysis Overlap Syndrome: A rare Adverse Reaction. Journal of Nepal Paediatric Society, 42(1), 144–146. https://doi.org/10.3126/jnps.v42i1.39225

Issue

Vol. 42 No. 1 (2022)

Section

Case Reports

License

Copyright (c) 2022 kavthekar, Amith k, ravikiran, Yoganand J Phulari

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