Lamotrigine Induced Severe Cutaneous Reaction

  • YB Roka Chief of Neurosurgery, Neuro Hospital, Biratnager
  • N Roka Chief Ophthalmologist, Golcha Eye Hospital, Biratnagar
  • HB Adhikari Medical Officer Neuro Hospital, Biratnagar
Keywords: AED, Epilepsy, Lamotrigine, Skin rash, Stevens-Johnson syndrome

Abstract

Antiepileptic drugs are used commonly by physicians, neurologist and neurosurgeons in Nepal. Lamotrigine is an effective antiepileptic drug used as an add-on and monotherapy for a variety of seizure types in both adults and children. Rashes due to AED including SJS and hypersensitivity syndrome leading to hospitalization occur in approximately 0.33% of adults and 0.8% in children. Reactions due to LTG alone occur in around 5.7% of cases. We report probably the first case of this reaction in a 12-year old girl with a brief discussion on its etiology and management.

J Nepal Paediatr Soc 2012;32(2):172-174

doi: http://dx.doi.org/10.3126/jnps.v32i2.5608

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Abstract
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Published
2012-10-01
How to Cite
Roka, Y., Roka, N., & Adhikari, H. (2012). Lamotrigine Induced Severe Cutaneous Reaction. Journal of Nepal Paediatric Society, 32(2), 172-174. https://doi.org/10.3126/jnps.v32i2.5608
Section
Brief Reports/Case Reports/Case Series