Bruton’s X-Linked Agammaglobulinemia Presenting as Chronic Monoarticular Arthritis

  • Mani Kant Kumar Assistant Professor, Narayan Medical College and Hospital, Jamuhar, Sasaram, Bihar
  • Pankaj Kumar Patel Assistant Professor, Department of Pathology, Narayan Medical College and Hospital, Jamuhar, Sasaram, Bihar
  • Mohammad Mahtab Ali Tahir Junior Resident, Department of Paediatrics, Narayan Medical College and Hospital, Jamuhar, Sasaram, Bihar
Keywords: Bruton’s X-linked Agammaglobulinemia, Chronic monoarticular arthritis, Btk gene

Abstract

Bruton’s X-Linked Agammaglobulinemia (XLA) is an X linked recessive primary immune deficiency disorder characterized by recurrent bacterial infections and failure to generate immunoglobulins of all isotypes due to the absence or profoundly decreased mature B cells and plasma cells, secondary to mutations in the Bruton’s tyrosine kinase (Btk) gene. The coexistence of chronic monoarticular arthritis in a patient with Bruton’s XLA has been described an uncommon presentation. We describe a 5 year-old boy with XLA and chronic monoarticular arthritis.

DOI: http://dx.doi.org/10.3126/jnps.v32i3.6183

J. Nepal Paediatr. SocVol.32(3) 2012 245-249

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Abstract
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Published
2013-02-23
How to Cite
Kumar, M., Patel, P., & Tahir, M. M. (2013). Bruton’s X-Linked Agammaglobulinemia Presenting as Chronic Monoarticular Arthritis. Journal of Nepal Paediatric Society, 32(3), 245-249. https://doi.org/10.3126/jnps.v32i3.6183
Section
Brief Reports/Case Reports/Case Series