Breakthrough infection after Covishield COVID-19 vaccine among health care workers at Patan Academy of Health Sciences, Nepal

Authors

DOI:

https://doi.org/10.3126/jpahs.v8i2.28833

Keywords:

Breakthrough Infection, Covishield COVID-19 Vaccine, Reinfection

Abstract

Introduction: Coronavirus Disease 2019 (COVID-19) vaccines have an important role in the control and prevention of the pandemic. However, infection after vaccination, though uncommon, has been reported after partial or complete immunization. This study aims to find out vaccine breakthrough infection after the Covishield COVID-19 vaccine.

Method: This cross-sectional survey was conducted among the health care workers (HCWs) from May 2021 to July 2021 at Patan Hospital, Patan Academy of Health Sciences, Nepal who received the Covishield vaccine. The data were collected using Google form and a printed questionnaire on COVID 19 breakthrough infection ≥2w after vaccination. The rate of breakthrough infection, hospitalization, and its association with age, gender, and working departments of HCWs was analyzed using SPSS. Ethical approval was obtained.

Result: Out of 1462 HCWs approached, 880 completed the survey, among which 819 (93.1%) had a completed vaccination status. Infection after the first and before the second dose was 164 (18.7% of 880) and after two doses 131 (16%). The breakthrough infection occurred in 83 (10.1% of 819). There was no statistically significant association of breakthrough infection with age, gender, and working department of HCWs. Total 74 (8.4%) were managed by admission in hospital.

Conclusion: The findings of this study reveal a low breakthrough infection rate after Covishield vaccination among HCWs at Patan Academy of Health Sciences, Kathmandu, Nepal. Overall, COVID-19 infection rates decreased after the first and second dose of the vaccine.

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Author Biographies

Jay Shah, Patan Academy of Health Sciences, Lalitpur, Kathmandu, Nepal

Professor, Department of Surgery, Patan Hospital

Priscilla Samson, Patan Academy of Health Sciences, Lalitpur, Kathmandu, Nepal

Associate Professor, Lalitpur Nursing Campus, School of Nursing and Midwifery

Nabees MS Pradhan, Patan Academy of Health Sciences, Lalitpur, Kathmandu, Nepal

Professor, Department of Orthopedics and Trauma Surgery, Patan Hospital

Ashis Shrestha, Patan Academy of Health Sciences, Lalitpur, Kathmandu, Nepal

Assistant Professor, Department of General Practice and Emergency Medicine, Patan Hospital

Shreekrishna Maharjan, Patan Academy of Health Sciences, Lalitpur, Kathmandu, Nepal

Associate Professpr, Department of Biochemistry and Molecular Lab Medicine, Patan Hospital

Shanta Dangol Shrestha, Patan Academy of Health Sciences, Lalitpur, Kathmandu, Nepal

Nursing Director, Patan Hospital

Sarala KC, Patan Academy of Health Sciences, Lalitpur, Kathmandu, Nepal

  1. Professor & Nursing Dean, Lalitpur Nursing Campus, School of Nursing and Midwifery

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Published

2021-08-31

How to Cite

Shah, J., Samson, P., Pradhan, N. M., Shrestha, A., Maharjan, S., Dangol Shrestha, S., & KC, S. (2021). Breakthrough infection after Covishield COVID-19 vaccine among health care workers at Patan Academy of Health Sciences, Nepal. Journal of Patan Academy of Health Sciences, 8(2), 10–17. https://doi.org/10.3126/jpahs.v8i2.28833

Issue

Section

COVID-19: Original Articles