Miescher’s cheilitis: A case report with literature review

Authors

  • Ram Chandra Adhikari Tribhuvan University Teaching Hospital, Kathmandu
  • Mahesh Shah Anandban Leprosy Hospital, Lalitpur

DOI:

https://doi.org/10.3126/jpn.v8i1.19465

Keywords:

Cheilitis, Lip, Melkersson-Rosenthal syndrome, Miescher’s,

Abstract

Miescher’s cheilitis is an inflammatory disorder characterized by chronic lip swelling due to granulomatous inflammation. It is rare disorder first described by Miescher in 1945. It is monosymptomatic form of Melkersson-Rosenthal syndrome. We report a case of Miescher’s cheilitis in a 59-year old lady presented with recurrent swelling and erythema of upper lip and submental area with no features of facial palsy and fissuring of tongue. Laboratory tests including serum complement C3, C4 and C1 esterase inhibitor functional were within normal limits. The biopsy from the upper lip revealed dermal edema, dilated lymphatic channels and multiple granulomas. After exclusion of other causes of orofacial granulomatosis, the diagnosis of Miescher’s cheilitis was made. Patient was treated with oral hydroxychloroquine and topical tacrolimus and mometasone cream with gradual improvement.

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Author Biographies

Ram Chandra Adhikari, Tribhuvan University Teaching Hospital, Kathmandu

Pathology

Mahesh Shah, Anandban Leprosy Hospital, Lalitpur

Dermatology

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Published

2018-04-03

How to Cite

Adhikari, R. C., & Shah, M. (2018). Miescher’s cheilitis: A case report with literature review. Journal of Pathology of Nepal, 8(1), 1313–1316. https://doi.org/10.3126/jpn.v8i1.19465

Issue

Section

Case Reports