Approach to native medical renal biopsy interpretation of glomerular disease

Authors

DOI:

https://doi.org/10.3126/jpn.v9i2.25664

Keywords:

Electron microscopy, Glomerulonephritis, Immunohistology, Renal biopsy

Abstract

Diverse pathogenetic mechanisms and clinical manifestation of renal diseases may produce the same renal morphologic pattern or variety of renal morphologic pattern can lead to the same clinical syndrome. The primary role of the renal biopsy is to provide a diagnosis and information about disease activity and chronicity. The systematic approach to native medical renal biopsy includes evaluation of the four compartments of the kidney sequentially (glomeruli, tubules, interstitium, and blood vessels). The diagnosis in renal pathology is an integrated process in which we must analyze all clinical data, light microscopy, immunohistology, and electron microscopy studies for diagnosis. The aim of the article is to describe the handling of the renal tissue in the anatomical pathology laboratory. It also provides the guideline to renal biopsy evaluation and approach to arrive at the diagnosis of glomerular diseases with similar clinical presentations.

Downloads

Download data is not yet available.
Abstract
525
PDF
912

Author Biography

Gopi Aryal, Mediciti Hospital, Lalitpur, Nepal

Professor, Department of Laboratory Medicine & Pathology

Downloads

Published

2019-09-29

How to Cite

Aryal, G., & Aryal, S. C. (2019). Approach to native medical renal biopsy interpretation of glomerular disease. Journal of Pathology of Nepal, 9(2), 1571–1579. https://doi.org/10.3126/jpn.v9i2.25664

Issue

Section

Review Articles