Primary synovial sarcoma thyroid: an unusual presentation

  • Pallavi Srivastava Dr Ram Manohar Lohia Institute of Medical Science, Uttar Pradesh, India
  • Nidhi Anand Dr Ram Manohar Lohia Institute of Medical Science, Uttar Pradesh, India https://orcid.org/0000-0003-1831-9063
  • Nuzhat Husain Dr Ram Manohar Lohia Institute of Medical Science, Uttar Pradesh, India
Keywords: Epithelial membrane antigen; Synovial sarcoma; Thyroid; Transducin-like enhancer of split-1

Abstract

Primary Synovial sarcoma of the thyroid gland is a rare sarcoma. We report a case of synovial sarcoma of the thyroid gland in a 2-yr-old boy presenting with a palpable progressively increasing neck mass, high resolution ultrasound revealed a heterogeneous lesion measuring 5 x 4 cm identified in the right lobe compressing the left lobe. A total thyroidectomy was performed and grossly both the lobes were involved. Histologically, the tumor was a biphasic synovial sarcoma which was confirmed by immunohistochemical markers showing positive expression for vimentin, Epithelial membrane antigen &Transducin-like enhancer of split-1. This is an unusual location for the occurrence of primary synovial sarcoma and aggressive nature the early diagnosis is difficult, and no definite treatment regimens are being defined due to the rarity of neoplasm.

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Author Biographies

Pallavi Srivastava, Dr Ram Manohar Lohia Institute of Medical Science, Uttar Pradesh, India

Department of Pathology

Nidhi Anand, Dr Ram Manohar Lohia Institute of Medical Science, Uttar Pradesh, India

Associate Professor,  Department of Pathology

 

Nuzhat Husain, Dr Ram Manohar Lohia Institute of Medical Science, Uttar Pradesh, India

 Professor and Head, Department of Pathology

Published
2020-09-30
How to Cite
Srivastava, P., Anand, N., & Husain, N. (2020). Primary synovial sarcoma thyroid: an unusual presentation. Journal of Pathology of Nepal, 10(2), 1776-1778. https://doi.org/10.3126/jpn.v10i2.28358
Section
Case Reports