Histomorphological patterns of skin adnexal tumours with an insight into molecular updates - A single institutional study
Keywords:Skin adnexal tumors, histopathology, molecular updates, categorization
Background: Skin adnexal tumors are a spectrum of benign and malignant tumors that differentiate toward or arise from the adnexal unit of the skin. These rare tumors pose a challenge in diagnosis, and often, a discrepancy is seen between clinical and histopathological diagnosis.
Materials and methods: This single institutional study was carried out among 36 patients who presented with swelling. An initial diagnosis was considered based on the clinical history followed by histopathological examination.
Results: Among the 36 patients, only 4 had malignant tumors. Among them, 3 had sebaceous differentiation, and 1 had apocrine and eccrine differentiation. Among the benign, 14 had follicular differentiation, 12 had apocrine and eccrine differentiation, and 6 had sebaceous differentiation. The clinic-pathological correlation was 65%.
Conclusions: An accurate diagnosis is not possible with just the clinical features. Histopathologic examination is considered the gold standard for diagnosis and categorization.
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Copyright (c) 2023 Sangeetha Kandasamy, Roopmala Murugan, Gramani Arumugam Vasugi, Kumudhini Priya Gunasekaran
This work is licensed under a Creative Commons Attribution 4.0 International License.