Metastatic cutaneous and subcutaneous lesions: Analysis of cases diagnosed on fine needle aspiration cytology

  • S Karki Department of pathology, Institute of Medicine, Kathmandu
  • R Pathak Department of pathology, Institute of Medicine, Kathmandu
  • U Manandhar Department of pathology, Institute of Medicine, Kathmandu
  • S Koirala Department of pathology, Institute of Medicine, Kathmandu
Keywords: Fine needle aspiration, Cutaneous metastases

Abstract

Background: Cutaneous and subcutaneous metastasis from an underlying primary, indicates a dismal outcome for patients. It is appropriate to use fine needle aspiration cytology as a minimally invasive method for diagnosis. This study emphasises the role of fine needle aspiration cytology in diagnosing metastatic skin nodules.

Materials and methods: This was a retrospective study in which the record of all patients subjected to fine needle aspiration cytology from April 2008 – Nov 2010 in the Department of Pathology, Tribhuvan University Teaching Hospital, were reviewed. Of 5,927 patients, 19 cases diagnosed as metastatic skin lesions were included in the study.

Results: Out of 19 patients with metastatic skin nodules, 9 patients had metastasis simultaneously with the primary and 8 cases were previously diagnosed. All metastases were from internal solid organ tumours with male to female ratio of 1.7:1. Lung carcinoma was the most common to metastasis in both sexes which included adenocarcinoma (5 cases) and squamous cell carcinoma (6 cases). Common sites for cutaneous/subcutaneous metastasis were the chest wall (9 cases) followed by abdomen (4 cases) and scalp (3 cases).

Conclusion: Fine needle aspiration cytology can diagnose a variety of skin lesions which may be supportive in diagnosing a metastasis in cases with known primaries or it may offer a clue to underlying malignancy in unsuspected cases.

Keywords: Fine needle aspiration; Cutaneous metastases

DOI: 10.3126/jpn.v1i1.4449

Journal of Pathology of Nepal (2011) Vol.1, 37-40  

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Karki, S., Pathak, R., Manandhar, U., & Koirala, S. (1). Metastatic cutaneous and subcutaneous lesions: Analysis of cases diagnosed on fine needle aspiration cytology. Journal of Pathology of Nepal, 1(1), 37-40. https://doi.org/10.3126/jpn.v1i1.4449
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