ACTH more than 2000 pg/ml; is it immunoassay interference or another matter?

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Keywords:

Adrenal Crisis, ACTH, Rifampicin

Abstract

Starting rifampicin in patients with Addison’s disease or adrenal tuberculosis may precipitate an adrenal crisis as a result of the induction of CYP 3A4 which in turn leads to increased breakdown of cortisol. We report this rare phenomenon to increase awareness among healthcare professionals. 

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Author Biographies

Vivek Pant, Samyak Diagnostic Pvt. Ltd. Lalitpur, Nepal

Department of Biochemistry

Santosh Pradhan, Samyak Diagnostic Pvt Ltd, Lalitpur, Nepal

Department of Biochemistry

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Published

2023-07-12

How to Cite

Pant, V., & Pradhan, S. (2023). ACTH more than 2000 pg/ml; is it immunoassay interference or another matter?. Journal of Pathology of Nepal, 13(1), 2026-2026. https://doi.org/10.3126/jpn.v13i1.54455

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How to Cite

Pant, V., & Pradhan, S. (2023). ACTH more than 2000 pg/ml; is it immunoassay interference or another matter?. Journal of Pathology of Nepal, 13(1), 2026-2026. https://doi.org/10.3126/jpn.v13i1.54455