Management of nitrobenzene poisoning in a resource-constrained setting: A case report

Authors

  • Subodh Bashyal Universal College of Medical Sciences, Bhairahawa, Nepal
  • Manoj Karki Universal College of Medical Sciences, Bhairahawa, Nepal
  • Sudhan Devkota Universal College of Medical Sciences, Bhairahawa, Nepal
  • Aprajita Sharma Universal College of Medical Sciences, Bhairahawa, Nepal
  • Binod Prasad Sah Universal College of Medical Sciences, Bhairahawa, Nepal
  • Niraj Kumar Jaiswal Universal College of Medical Sciences, Bhairahawa, Nepal
  • Bidhata Rayamajhi Universal College of Medical Sciences, Bhairahawa, Nepal
  • Sabu Pokharel Universal College of Medical Sciences, Bhairahawa, Nepal

DOI:

https://doi.org/10.3126/jucms.v14i01.94011

Keywords:

Nitrobenzene poisoning, Methemoglobinemia, Resource-constrained setting, Pesticide

Abstract

INTRODUCTION

Nitrobenzene poisoning is an uncommon but potentially fatal cause of acquired methemoglobinemia, particularly in agricultural regions. We report an 18-year-old male presenting with acute hypoxia, cyanosis, and refractory low oxygen saturation following unknown pesticide ingestion. Despite limited diagnostic resources, characteristic clinical features, chocolate-colored blood, and a marked saturation gap supported the diagnosis of methemoglobinemia. Prompt empirical treatment with oxygen, methylene blue, and ascorbic acid resulted in rapid recovery. This case highlights the importance of clinical recognition and early intervention in suspected nitrobenzene poisoning, especially in resource-limited settings.

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Author Biographies

Subodh Bashyal, Universal College of Medical Sciences, Bhairahawa, Nepal

Department of Internal Medicine

Manoj Karki, Universal College of Medical Sciences, Bhairahawa, Nepal

Department of Internal Medicine

Sudhan Devkota, Universal College of Medical Sciences, Bhairahawa, Nepal

Department of Internal Medicine

Aprajita Sharma, Universal College of Medical Sciences, Bhairahawa, Nepal

Department of Internal Medicine

Binod Prasad Sah, Universal College of Medical Sciences, Bhairahawa, Nepal

Department of Internal Medicine

Niraj Kumar Jaiswal, Universal College of Medical Sciences, Bhairahawa, Nepal

Department of Internal Medicine

Bidhata Rayamajhi, Universal College of Medical Sciences, Bhairahawa, Nepal

Department of Internal Medicine

Sabu Pokharel, Universal College of Medical Sciences, Bhairahawa, Nepal

Department ol Internal Medicine

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Published

2026-05-22

How to Cite

Subodh Bashyal, Manoj Karki, Sudhan Devkota, Aprajita Sharma, Binod Prasad Sah, Niraj Kumar Jaiswal, … Sabu Pokharel. (2026). Management of nitrobenzene poisoning in a resource-constrained setting: A case report. Journal of Universal College of Medical Sciences, 14(01), 49–52. https://doi.org/10.3126/jucms.v14i01.94011

Issue

Section

Case Reports