Role of HbA1c as a Marker of Dyslipidemia in Patients with Type 2 Diabetes Mellitus Visiting Tertiary Health Care Center

Authors

  • Prachi Rayamajhi Assistant Professor, Department of Biochemistry, Nepalese Army Institute of Health Sciences, Bhandarkhal, Swoyambhu, Kathmandu, Nepal
  • Salina Pradhananga Assistant Professor, Department of Biochemistry, Nepalese Army Institute of Health Sciences, Bhandarkhal, Swoyambhu, Kathmandu, Nepal
  • Arabinda Mohan Bhattarai Assistant Professor, Department of Biochemistry, Nepalese Army Institute of Health Sciences, Bhandarkhal, Swoyambhu, Kathmandu, Nepal

DOI:

https://doi.org/10.3126/mjsbh.v22i1.54197

Keywords:

Type 2 Diabetes, Dyslipidemia, HbA1c

Abstract

Introduction: Diabetic patients with accompanied (but often unnoticed) dyslipidemia are soft targets of cardiovascular deaths. Glycated hemoglobin (HbA1c) is a routinely used marker for long-term glycemic control. This investigation is an attempt to evaluate the diagnostic value of HbA1c in predicting diabetic dyslipidemia.

Methods: This was a cross-sectional study where the sera were analyzed for HbA1c, fasting blood glucose (FBG), total cholesterol, triglycerides, highdensity lipoprotein cholesterol (HDL) and low-density lipoprotein cholesterol. SPSS version 23.0 was used to analyze the data.

Results: The levels of HbA1c did not differ significantly between males and females whereas male patients had significantly higher fasting blood glucose than females. There was a highly significant correlation between HbA1c and FBG. Both HbA1c and fasting blood glucose exhibited direct correlations with cholesterol, TG and LDL and inverse correlation with HDL; the magnitude of significance for all these lipid parameters being greater with HbA1c than fasting blood glucose.

Conclusions: HbA1c can provide valuable information about the circulating lipids beside its primary role in monitoring long term glycemic control.

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Published

2023-10-23

How to Cite

Rayamajhi, P., Pradhananga, S. ., & Mohan Bhattarai, A. . (2023). Role of HbA1c as a Marker of Dyslipidemia in Patients with Type 2 Diabetes Mellitus Visiting Tertiary Health Care Center. Medical Journal of Shree Birendra Hospital, 22(1), 39–46. https://doi.org/10.3126/mjsbh.v22i1.54197

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Section

Original Articles