Refractory True Torsade de Pointes after Adalimumab Therapy in a Patient with Crohn’s Disease Successfully Treated by Stellate Ganglion Block: A Case Report

Authors

  • Vijay Yadav Department of Cardiology, Manmohan Cardiothoracic Vascular and Transplant Center, Institute of Medicine, Tribhuvan University, Nepal https://orcid.org/0000-0002-3837-3828
  • Ratna Mani Gajurel Department of Cardiology, Manmohan Cardiothoracic Vascular and Transplant Center, Institute of Medicine, Tribhuvan University, Nepal
  • Chandra Mani Poudel Department of Cardiology, Manmohan Cardiothoracic Vascular and Transplant Center, Institute of Medicine, Tribhuvan University, Nepal
  • Sanjeev Thapa Department of Cardiology, Manmohan Cardiothoracic Vascular and Transplant Center, Institute of Medicine, Tribhuvan University, Nepal
  • Bhawani Manandhar Department of Cardiology, Manmohan Cardiothoracic Vascular and Transplant Center, Institute of Medicine, Tribhuvan University, Nepal
  • Kundan Raj Pandey Department of Cardiology, Manmohan Cardiothoracic Vascular and Transplant Center, Institute of Medicine, Tribhuvan University, Nepal
  • Dhiraj Poudel Department of Cardiology, Manmohan Cardiothoracic Vascular and Transplant Center, Institute of Medicine, Tribhuvan University, Nepal
  • Ninadini Shrestha Department of Anesthesiology, Maharajgunj Medical Campus, Institute of Medicine, Tribhuvan University, Nepal

DOI:

https://doi.org/10.3126/nhj.v22i2.85801

Keywords:

Adalimumab, True Torsade de Pointes, Electrical storm, Stellate Ganglion Block

Abstract

Several studies have reported the occurrence of new-onset cardiomyopathy and ventricular arrhythmias (VAs) after the administration of Adalimumab. We report the case of a 20-year-old male who presented himself with the features of dilated cardiomyopathy and a left ventricular ejection fraction of 10-15% after two weeks of administration of adalimumab. During the hospital stay, he developed multiple episodes of VAs (true torsade de pointes) in the form of electrical storm, which were refractory to both pharmacological and electrical interventions. He eventually underwent ultrasonographic guided left-sided stellate ganglion block with 6 mL of 0.2% bupivacaine and 40 mg of methylprednisolone injection. There was no recurrence of ventricular arrhythmias for 72 hours after the procedure.

Downloads

Download data is not yet available.
Abstract
20
PDF
13
Covber NHJ

Downloads

Published

2025-10-30

How to Cite

Yadav, V., Gajurel, R. M., Poudel, C. M., Thapa, S., Manandhar, B., Pandey, K. R., … Shrestha, N. (2025). Refractory True Torsade de Pointes after Adalimumab Therapy in a Patient with Crohn’s Disease Successfully Treated by Stellate Ganglion Block: A Case Report. Nepalese Heart Journal, 22(2), 83–86. https://doi.org/10.3126/nhj.v22i2.85801

Issue

Vol. 22 No. 2 (2025)

Section

Case Reports

License

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format, so long as attribution is given to the creator. The license allows for commercial use.