Creutzfeldt-Jackob disease: A Case Report with MRI (DWI) Findings

  • Hari Om Joshi Bhaktapur Hospital, Bhaktapur, Nepal
  • Tong Dan The First Hospital of Jilin University, Changchun, Jilin, China
  • Ting Tang Yuan The First Hospital of Jilin University, Changchun, Jilin, China
  • Ajit Thapa TUTH Hospital, Kathmandu, Nepal
  • Jyotsna Shakya Manmohan Memorial Institute of Health Sciences, Kathmandu, Nepal
Keywords: Creutzfeldt-Jakob disease, Transmissible Spongiform Encephalopathy

Abstract

Transmissible Spongiform Encephalopathy is sub-acute transmissible neurodegenerative disease which affects both human and animals. Among those that affect humans, Creutzfeldt- Jakob disease is the most common. This disease has a genetic basis and characteristic of an infectious disease. Magnetic Resonance Imaging is an important tool in diagnosis of Creutzfeldt-Jakob disease and can assist especially in the early stages of the disease, when the clinical features might not be typical and Electroencephalogram shows normal or nonspecific abnormalities. Newer Magnetic Resonance Imaging techniques such as Diffusion Weighted Imaging have shown to be more sensitive in detecting this disease at its early stage. We report a single case of probable Creutzfeldt-Jakob disease and its peculiar findings on brain magnetic resonance imaging.

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Author Biographies

Hari Om Joshi, Bhaktapur Hospital, Bhaktapur, Nepal

Consultant Radiologist, Department of Radiology,

Tong Dan, The First Hospital of Jilin University, Changchun, Jilin, China

Department of Radiology

Ting Tang Yuan, The First Hospital of Jilin University, Changchun, Jilin, China

Department of Radiology

Ajit Thapa, TUTH Hospital, Kathmandu, Nepal

Department of Radiology

Jyotsna Shakya, Manmohan Memorial Institute of Health Sciences, Kathmandu, Nepal

Department of Laboratory Medicine

Published
2019-09-05
How to Cite
Joshi, H., Dan, T., Yuan, T., Thapa, A., & Shakya, J. (2019). Creutzfeldt-Jackob disease: A Case Report with MRI (DWI) Findings. Nepal Journal of Medical Sciences, 4(2), 32-35. https://doi.org/10.3126/njms.v4i2.25476
Section
Case Reports