Helicobacter Pylori Infection Among Patients Undergoing Upper Gastrointestinal Endoscopy For Dyspepsia

Authors

DOI:

https://doi.org/10.3126/njms.v6i2.42399

Keywords:

Biopsy, Dyspepsia, Endoscopy, Gastrointestinal, Helicobacter Pylori

Abstract

Introduction:

Helicobacter pylori is associated with the pathogenicity of gastroduodenal mucosal lesions, ulcers, and gastric cancers. The present study was undertaken to study the prevalence of H. pylori infection among patients undergoing upper gastrointestinal (UGI) endoscopy for dyspepsia in the Nepalese population.

Methods:

A cross-sectional, hospital-based study was conducted among patients presenting with dyspepsia. Each study patient underwent upper gastrointestinal endoscopy followed by a rapid urease test or histopathology from the biopsy sample for H. pylori detection. Data analysis was done by SPSS 20.

Results:

The mean age of the patients was 43±11.65 years (M: F=1.4:1) with male predominance. The prevalence of H. pylori infection was 53.2% among the dyspeptic patients undergoing UGI endoscopy. The H. pylori infection was significantly associated with gastritis, duodenitis, gastric ulcer, duodenal ulcer, and gastric cancer (p <0.05).

Conclusion:

This study demonstrates a high prevalence of H. pylori among patients undergoing UGI endoscopy for dyspepsia.

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Author Biographies

Subash Bhattarai , Manipal College of Medical Sciences

Associate Professor, Department of Medicine

Durga Dhungana, Manipal College of Medical Sciences

Assistant Professor, Department of Medicine

Sudeep Regmi, Manipal College of Medical Sciences

Lecturer, Department of Pathology

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Published

2021-12-31

How to Cite

Bhattarai , S., Dhungana, D., & Regmi, S. (2021). Helicobacter Pylori Infection Among Patients Undergoing Upper Gastrointestinal Endoscopy For Dyspepsia. Nepal Journal of Medical Sciences, 6(2), 12–17. https://doi.org/10.3126/njms.v6i2.42399

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Original Articles