Clinical manifestations of hypothyroidism in residents of western region of Nepal: A case control study
Keywords:Hypothyroidism, common, signs, symptoms, case control studies
Background: This study was designed for the evaluation of the difference in the common signs and symptoms of hypothyroidism in our population from already available literature.
Methods: In this study we have compared the symptoms and signs of hypothyroid and euthyroid patients visiting to Gandaki Medical College Teaching Hospital (GMCTH) from April 2011 to October 2011. We compared the 18 common signs and symptoms of hypothyroidism in our patients and analyzed by SPSS software.
Results: Of the 2483 patients visiting to the GMCTH, 665 patients were included in the study and were examined. After the laboratory investigations, 98 were identified as the cases of hypothyroidism, the rest were declared as euthyroid and selected as controls. Lethargy, cold intolerance, constipation and paresthesia were the commonest symptom while facial oedema and bradycardia were the most prevalent sign in our population.
Conclusions: The most common signs and symptoms of hypothyroidism in the western region of Nepal (that is one of the iodine deficient areas in Nepal) were different from other studies. It seems that strong clinical suspicion on the basis of symptoms and signs elicited by physicians and laboratory confirmation are the only reliable methods for diagnosis of hypothyroidism.
Nepal Journal of Medical Sciences | Volume 02 | Number 01 | Jan-Jun 2013 | Page 62-65DOI: http://dx.doi.org/10.3126/njms.v2i1.7655
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