Preoperative Factors Associated with Postoperative Diabetes Insipidus after Transsphenoidal Pituitary Adenectomy

  • Sagar Koirala Department of Neurosurgery Upendra Devkota Memorial National Institute of Neurological and Allied Sciences Bansbari, Kathmandu https://orcid.org/0000-0003-4625-2011
  • Suresh Bishokarma Department of Neurosurgery Upendra Devkota Memorial National Institute of Neurological and Allied Sciences Bansbari, Kathmandu
  • Dinesh Nath Gongal Department of Neurosurgery Upendra Devkota Memorial National Institute of Neurological and Allied Sciences Bansbari, Kathmandu
Keywords: Transsphenoidal pituitary adenectomy, Diabetes insipidus

Abstract

Transsphenoidal pituitary adenectomy is the gold standard method of treatment of pituitaryadenomas. Post-operative diabetes insipid sis one of the common complication of this procedure. In this study we have analyzed pre-operative factors that may be associated with onset of diabetes insipid us following this procedure. A retrospective study of five years was conducted in a tertiary neurosurgical center. Histologically proven cases of pituitary adenomas who underwent transsphenoidalpituitary adenectomy were included in the study. Age and sex of the patients along with size and functional type of tumor were analyzed to see if they predicted the occurrence of diabetesinsipidus post-operatively. Out of 49 cases who underwent transsphenoidalpituitary surgery, 46 cases were proven to be pituitary adenomas histologically. There was male preponderance with male to female ratio of2:1. Age ranged from 15 to 72 with median age of 37 years. Nonfunctional, prolactinomas and growth hormone secreting tumors, were 25, 16and 4 in number. Median size of the tumor was2.35 in largest diameter. Out of these patients13 (28%) patients developed diabetes insipid us. Age, sex of the patient, size of the tumor and functional type of the tumor did not predict the incidence. Age, sex of the patient, size of the tumor and functional type of the tumor do not predict the incidence of diabetes insipid us post-operatively in patients undergoing transsphenoidal pituitaryadenectomy.

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Author Biographies

Sagar Koirala, Department of Neurosurgery Upendra Devkota Memorial National Institute of Neurological and Allied Sciences Bansbari, Kathmandu

Neurosurgeon

Suresh Bishokarma, Department of Neurosurgery Upendra Devkota Memorial National Institute of Neurological and Allied Sciences Bansbari, Kathmandu

Neurosurgeon

Dinesh Nath Gongal, Department of Neurosurgery Upendra Devkota Memorial National Institute of Neurological and Allied Sciences Bansbari, Kathmandu

Professor

Published
2019-12-31
How to Cite
Koirala, S., Bishokarma, S., & Gongal, D. (2019). Preoperative Factors Associated with Postoperative Diabetes Insipidus after Transsphenoidal Pituitary Adenectomy. Nepal Journal of Neuroscience, 16(3), 55-57. https://doi.org/10.3126/njn.v16i3.27359
Section
Short Communication