Fetal Ventricular Dilation; prelude to Dandy-Walker Syndrome and Hydrocephalus: Synopsis of Two Case Reports

Authors

  • Adam Moyosore AFODUN Department of Anatomy and Cell Biology, Faculty of Health Sciences, Busitema University, Uganda
  • Khadijah Kofoworola Quadri Department of Physiology, Faculty of Basic Medical Sciences, University of Ilorin, Nigeria.
  • Mustapha Akajewole MASUD Department of Human Anatomy, School of Health and Medical Sciences, State University of Zanzibar, Zanzibar, Tanzania. https://orcid.org/0000-0002-3688-9994
  • Sulaiman Oluwadare Sheu Department of Physiology, Faculty of Biomedical Sciences, Kampala International University, Uganda
  • Katembo Sikakulya Franck Department of Surgery, Faculty of Clinical Medicine and Dentistry, Kampala International University, Uganda
  • Olatayo Segun Okeniran Department of Anatomy, Faculty of Biomedical Sciences, Kampala International University, Uganda
  • Raymond Joseph Malinga Department of Anatomy and Cell Biology, Faculty of Health Sciences, Busitema University, Uganda
  • Julius Namasake Wandabwa Department of Obstetrics and Gynecology, Faculty of Health Sciences, Busitema University, Uganda

DOI:

https://doi.org/10.3126/njn.v19i1.40252

Keywords:

ultrasound, CSF, brain, fetal, transfontanelle

Abstract

Accurate measurement of the 3rd and 4th ventricles is important in cases of prenatal and postnatal diagnosis of suspected cranial anomalies. Ventricular dilation occurs with excess fluid in the embryologic ventricles during brain development, we make a comparative analysis of two case reports on a 23rd-week fetus and a 10-month-old neonate. Ultrasound findings related to horns and ventricular system through transfontanelle ultrasound (excluding any > 95th error margin and < 5th percentile) can be utilized for a specific diagnosis of ventricular dilation. Hydrocephalus is defined as the accumulation of excessive CSF resulting in dilation of the cerebrospinal compartment in the calvaria; which can be acquired or congenital in origin. Hydrocephalus can also be seen due to obstructed flow, faulty absorption, and overproduction of CSF (in the subarachnoid space) by a choroid plexus papilloma. The diameter of the anterior horn of the RT and LT (hydrocephalic) lateral ventricles measured 15.3mm and 14.1mm respectively, far above the threshold for normal (control) neonates / RT and LT (anterior) lateral ventricles averaging 2.40mm and 2.51mm. These documented findings indicate the excellent agreement between fetal brain sonography in the diagnosis of fetal ventriculomegaly (anterior horn/ 10.4mm) and dilation (combined 40.8mm). Mean Head Circumference (MHC) for neonatal hydrocephalus was 44.2cm far above the normal average of 36.7cm. When we assessed the clinical benchmark of 10mm or (>19mm) for the neonate ventricle, it was far above the normal range (greater than > 95th percentile value).

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Published

2022-03-15

How to Cite

AFODUN, A. M., Quadri, K. K., MASUD, M. A., Sheu, S. O., Franck, K. S., Okeniran, O. S., Malinga, R. J., & Wandabwa, J. N. (2022). Fetal Ventricular Dilation; prelude to Dandy-Walker Syndrome and Hydrocephalus: Synopsis of Two Case Reports. Nepal Journal of Neuroscience, 19(1), 59–65. https://doi.org/10.3126/njn.v19i1.40252

Issue

Section

Case Report