Maternal serum triglyceride at midpregnancy and newborn weight in nondiabetic and normal BMI women

Authors

  • Leila Sekhavat Department of Obstetrics & Gynecology, Shaheed Sadoughi hospital, Shaheed Sadoughi University of Medical Sciences and Health Services, Yazd, Iran
  • Fatemah Zare Department of Obstetrics & Gynecology, Shaheed Sadoughi hospital, Shaheed Sadoughi University of Medical Sciences and Health Services, Yazd, Iran
  • Sedighah Akhavan Karbasi Department of Pediateric, Shaheed Sadoughi hospital, Shaheed Sadoughi University of Medical Sciences and Health Services, Yazd, Iran

Keywords:

Birth weight, hypertriglyceridemia, nondiabeic pregnant, normal BMI

Abstract

Aim: To determine whether elevated midpregnancy (24 -28 Gestational weeks) maternal serum lipid levels predict the risk of macrosomia in non-diabetic women.

Methods: Nondiabetic pregnant women (who had negative diabetic screens) were enrolled. Fasting serum triglyceride, and total cholesterol levels were measured at 24-28 weeks gestation. We tested the association between maternal variables and birth weight by univariable analysis. We also used multiple logistic regression analysis to determine whether maternal hyperlipidemia is a risk factor for having an LGA infant.

Results: We enrolled 190 subjects. Among measured maternal lipids, only triglyceride levels correlated with birth weight in univariable analysis (r2 = 0.40, P = .000). Logistic regression analysis showed that fasting maternal hypertriglyceridemia was the significant predictor of macrosomia, independent of maternal weight gain and fasting plasma glucose levels. (Odds ratio 11.2; 95% confidence interval 1.5, 31.2; P = .01).

Conclusion: In nondiabetic women, fasting triglyceride levels at midpregnancy correlated positively with newborn weight at term.

Keywords: Birth weight, hypertriglyceridemia, nondiabeic pregnant, normal BMI   

doi:10.3126/njog.v3i1.1434

NJOG 2008 May-June; 3(1): 19 - 23

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Author Biography

Leila Sekhavat, Department of Obstetrics & Gynecology, Shaheed Sadoughi hospital, Shaheed Sadoughi University of Medical Sciences and Health Services, Yazd, Iran

Leila Sekhavat, MD
Department of Obstetrics & Gynecology, Shahid Sedughi Hospital,
Shahid Sedughi University of Medical Sciences and Health Services, Yazd, Iran.
Email: sekhavat@ssu.ac.ir
Fax No: 00983518224100, Tel: 00983518224001; Cell No. 00981525637

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How to Cite

Sekhavat, L., Zare, F., & Karbasi, S. A. (2008). Maternal serum triglyceride at midpregnancy and newborn weight in nondiabetic and normal BMI women. Nepal Journal of Obstetrics and Gynaecology, 3(1), 19–23. Retrieved from https://www.nepjol.info/index.php/NJOG/article/view/1434

Issue

Vol. 3 No. 1 (2008)

Section

Original Articles

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