Relationship between Time Interval from Admission to Delivery and Obstetrics Outcomes in Eclampsia/Severe Preeclampsia

Abstract

Aims: The purpose of this study was to find out the time interval from admission to delivery in eclamptic/ severe preeclamptic mothers and see the relationship to their obstetrics (maternal and fetal) outcomes.

Methods: A retrospective case review was conducted at Nepalgunj Medical College, Teaching hospital, Nepalgunj. About 152 mothers with eclampsia/severe preeclampsia and postpartum eclampsia whom received either loading or both loading and maintenance doses of Magnesium Sulfate, while they were admitted to the hospital from 1^stJanuary 2011 to 31^st December 2015. Out of them, 132 were eclampsia/severe preeclampsia (antepartum / intrapartum) and 20 mothers were postpartum eclampsia were enrolled in the study. Descriptive analysis was used by reviewing medical records and Maternity registers. A 95% CI and P-value of <0.05 were considered as statistically significant.

Results: Among 132 mothers, 53 (40.1%), 35 (26.5%) and 44 (33.3%) mothers delivered within 2 hours, 6 hours and ≥12 hours respectively. Ninety seven (73.4%) mothers underwent caesarean section, 27 (20.4%) had spontaneous vertex delivery 8(6%) underwent assisted vaginal deliveries. Out of 139 births there were 118 (84.8%) live births; 21 (15.1%) still births. The apgar score ≥7 at 5 minutes was seen in 81(58.2%) babies and low apgar <7 was seen in 37(26.6%) babies. and no evidence of live apgar "0" was seen in 23(16.5%).There were 2 neonatal deaths. Eleven still births in 2 hours, 4 in 6 hours and 6 in≥12 hours of admission were noted .Among 152 mothers including postpartum 20(13.1%) eclampsia, complications developed in 51 (33.5%) mothers. Maternal deaths were 2(1.3%).

Conclusions: There is no significant difference in obstetrics outcomes in early (2 hour), later (6 hours) and late (≥12 hours) delivery of eclamptic/severe preeclamptic mothers.