Risk factors and clinico-pathological profile of female genital tract malignancies at BPKIHS
Aims: To evaluate the risk factors and clinico-pathological profile of patients with female genital tract malignancy.
Methods: It was a prospective descriptive study of female genital tract malignancy conducted from December 2019 to December 2020 in the Department of Gynaecology, BPKIHS.
Results: Out of 61 cases, cervical cancer was the most common cancer (56.0%) followed by ovarian cancer (21.0%) and gestational trophoblastic neoplasia (13.0%). The mean age of patients was 50.82±12.81 years. 38 (62.3%) were postmenopausal; 59 (96.7%) had good performance status at presentation (ECOG 1 and 2); 41 (67.2%) had early stage disease (stage I and II). 36 (59.0%) were referred outside for further treatment and majority belonged to cervical cancer (n=29;80.5%) for radiotherapy services. Eight (13.1%) patients had disease recurrence and one patient (1.6%) had death during the study duration. Among patients with cervical cancer, the mean age at marriage and at first pregnancy were 17.24±2.32 years and 19.47±2.51 years respectively. Majority of them had poor local hygiene (n=27; 79.4%). The most common presentation was post menopausal bleeding (n=29; 85.3%) and most common histology was squamous cell carcinoma (n=30; 88.3%).
Conclusions: Cervical cancer is the most common female genital tract cancer followed by ovarian and gestational trophoblastic tumor.
Keywords: clinico-pathological, female, genital tract, malignancy, risk factors.
How to Cite
Copyright (c) 2022 Ramesh Shrestha, Soniya Dulal, Purbesh Adhikari, Anamika Das, Manisha Chhetry, Sapana Shrestha, Niraj Regmi, Pritha Basnet, Tulasha Basnet, Achala Thakur
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Copyright on any research article in the Nepal Journal of Obstetrics and Gynaecology is retained by the author(s).
The authors grant the Nepal Journal of Obstetrics and Gynaecology a license to publish the article and identify itself as the original publisher.
Articles in the Nepal Journal of Obstetrics and Gynaecology are Open Access articles published under the Creative Commons CC BY-NC License (https://creativecommons.org/licenses/by-nc/4.0/)This license permits use, distribution and reproduction in any medium, provided the original work is properly cited, and it is not used for commercial purposes.