Risk factors and clinico-pathological profile of female genital tract malignancies at BPKIHS

Authors

  • Ramesh Shrestha Department of Obstetrics and Gynaecology, B. P. Koirala Institute of Health Sciences, Dharan, Nepal
  • Soniya Dulal Medical Oncology, B. P. Koirala Institute of Health Sciences, Dharan, Nepal
  • Purbesh Adhikari Pathology, B. P. Koirala Institute of Health Sciences, Dharan, Nepal
  • Anamika Das Department of Obstetrics and Gynaecology, B. P. Koirala Institute of Health Sciences, Dharan, Nepal
  • Manisha Chhetry Department of Obstetrics and Gynaecology, B. P. Koirala Institute of Health Sciences, Dharan, Nepal
  • Sapana Shrestha Department of Midwifery Nursing, Purbanchal University School of Health Sciences
  • Niraj Regmi Radiology, B. P. Koirala Institute of Health Sciences, Dharan, Nepal
  • Pritha Basnet Department of Obstetrics and Gynaecology, B. P. Koirala Institute of Health Sciences, Dharan, Nepal
  • Tulasha Basnet Department of Obstetrics and Gynaecology, B. P. Koirala Institute of Health Sciences, Dharan, Nepal
  • Achala Thakur Department of Obstetrics and Gynaecology, B. P. Koirala Institute of Health Sciences, Dharan, Nepal

DOI:

https://doi.org/10.3126/njog.v17i34.48053

Keywords:

clinico-pathological, female, genital tract, malignancy, risk factors

Abstract

Aims: To evaluate the risk factors and clinico-pathological profile of patients with female genital tract malignancy.

Methods: It was a prospective descriptive study of female genital tract malignancy conducted from December 2019 to December 2020 in the Department of Gynaecology, BPKIHS.

Results: Out of 61 cases, cervical cancer was the most common cancer (56.0%) followed by ovarian cancer (21.0%) and gestational trophoblastic neoplasia (13.0%). The mean age of patients was 50.82±12.81 years. 38 (62.3%) were postmenopausal; 59 (96.7%) had good performance status at presentation (ECOG 1 and 2); 41 (67.2%) had early stage disease (stage I and II). 36 (59.0%) were referred outside for further treatment and majority belonged to cervical cancer (n=29;80.5%) for radiotherapy services. Eight (13.1%) patients had disease recurrence and one patient (1.6%) had death during the study duration. Among patients with cervical cancer, the mean age at marriage and at first pregnancy were 17.24±2.32 years and 19.47±2.51 years respectively. Majority of them had poor local hygiene (n=27; 79.4%). The most common presentation was post menopausal bleeding (n=29; 85.3%) and most common histology was squamous cell carcinoma (n=30; 88.3%).

Conclusions: Cervical cancer is the most common female genital tract cancer followed by ovarian and gestational trophoblastic tumor.

Keywords: clinico-pathological, female, genital tract, malignancy, risk factors.

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Published

2022-12-28

How to Cite

Shrestha, R., Dulal, S., Adhikari, P., Das, A., Chhetry, M., Shrestha, S., Regmi, N., Basnet, P., Basnet, T., & Thakur, A. (2022). Risk factors and clinico-pathological profile of female genital tract malignancies at BPKIHS. Nepal Journal of Obstetrics and Gynaecology, 17(1), 28–38. https://doi.org/10.3126/njog.v17i34.48053

Issue

Vol. 17 No. 1 (2022)

Section

Original Articles

License

Copyright (c) 2022 Ramesh Shrestha, Soniya Dulal, Purbesh Adhikari, Anamika Das, Manisha Chhetry, Sapana Shrestha, Niraj Regmi, Pritha Basnet, Tulasha Basnet, Achala Thakur

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