Role of Sonoelastography in Differentiating Benign and Malignant Breast Lesions: A Prospective Study Comparing Elasticity Contrast Index and Tsukuba Score

Authors

  • Amlendu Kumar Anand Diagnostics, Sitamarhi, Bihar, India
  • Anamika Jha Tribhuvan University Teaching Hospital, Kathmandu, Nepal
  • Pradeep Raj Regmi Tribhuvan University Teaching Hospital, Kathmandu, Nepal
  • Ghanshyam Gurung Tribhuvan University Teaching Hospital, Kathmandu, Nepal

DOI:

https://doi.org/10.3126/njr.v14i1.64625

Keywords:

Breast, Elasticity, Elasticity Imaging Techniques, Sonoelastography, Ultrasonography

Abstract

Introduction: Breast cancer is the most common cancer occurring in women globally which is potentially curable if detected early. Ultrasound elastography is a dynamic technique that estimates tissue stiffness to differentiate between benign and malignant masses. Our study aimed to determine and compare the diagnostic accuracy of B mode Sonography, Elasticity contrast index, and Tsukuba score in differentiating malignant and benign breast masses.

Methods: This was a prospective cross-sectional study done including 110 lesions in 102 patients in the age group of 15-73 years. The solid breast lesions seen on sonography were categorized according to the American College of Radiology Breast Imaging Reporting and Data System (ACR BI-RADS) and further evaluated with elastography using both Elasticity Contrast Index (ECI) and Tsukuba score with pathological diagnosis taken as the gold standard. The cut-off value of ECI was obtained. The diagnostic accuracy of B-mode sonography, ECI, and Tsukuba score was compared.

Results: We found that B-mode sonography had a sensitivity of 85.7%, specificity of 100%, and accuracy of 96.9 %. The accuracy of Tsukuba scores for differentiating benign and malignant lesions was 81.2%. The cut-off value of ECI obtained was 2.8 and the accuracy was 81.8%. A statistically significant correlation (p < 0.05) existed between sonographic diagnosis, ECI, and Tsukuba score.

Conclusions: B mode sonography had the highest diagnostic accuracy while ECI and Tsukuba scores were comparable. ECI can be used for breast masses using a cut-off of 2.8 to differentiate benign from malignant.

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Author Biographies

Amlendu Kumar, Anand Diagnostics, Sitamarhi, Bihar, India

Chairperson, Department of Radiology

Anamika Jha, Tribhuvan University Teaching Hospital, Kathmandu, Nepal

Assistant Professsor, Department of Radiology

Pradeep Raj Regmi, Tribhuvan University Teaching Hospital, Kathmandu, Nepal

Assistant Professsor, Department of Radiology

Ghanshyam Gurung, Tribhuvan University Teaching Hospital, Kathmandu, Nepal

Professor, Department of Radiology

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Published

2024-04-25

How to Cite

Kumar, A., Jha, A., Regmi, P. R., & Gurung, G. (2024). Role of Sonoelastography in Differentiating Benign and Malignant Breast Lesions: A Prospective Study Comparing Elasticity Contrast Index and Tsukuba Score. Nepalese Journal of Radiology, 14(1), 16–21. https://doi.org/10.3126/njr.v14i1.64625

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Original Articles