Gall bladder cancer: A single center experience

  • Sushil Bahadur Rawal Nepalese Army Institute of Health Sciences
  • Kunda Bikram Shah Nepalese Army Institute of Health Sciences
  • Dhana Bahadur Shrestha Nepalese Army Institute of Health Sciences
  • Srijan Malla Nepalese Army Institute of Health Sciences
  • Jyoti Rayamajhi Nepalese Army Institute of Health Sciences
  • Manoj Kumar Jha Nepalese Army Institute of Health Sciences
  • Anup Thapa Nepalese Army Institute of Health Sciences
Keywords: Gall bladder cancer, nepal, radical surgery

Abstract

Introduction Gallbladder cancer (GBC) is the most common malignancy of the biliary tract, which is increasing in Southeast Asia. An early diagnosis is crucial for curative surgical resection. However, patients present late because at an early stage the initial symptoms are non- specific. Radical surgery is a challenging operation, and should be carried out only if R0 resection is feasible.

Objectives: The aim of this study was to analyse the patient profile, clinical presentation and peri-operative outcome of patients who underwent various surgeries for GBC.

Methodology: Patients who had undergone surgery for GBC at our center over a 7 year period were identified from our database. A retrospective analysis from prospectively collected data was done. We analysed the outcome of these patients over the study period.

Results: Forty-four patients underwent surgery for GBC. There was a female preponderance (34 patients; 77%) and the mean age of the patients was 54 years (range 22-76 years). Thirty-six patients (82%) were diagnosed pre-operatively. Extended cholecystectomy (either segment IVb/V or 2cm nonanatomical wedge resection of the liver) with standard lymph node clearance was performed in 35 patients (79%). Peri-operative complications was seen in 11 patients (25%) and in hospital mortality was seen in 2 patients (4.5%)

Conclusion: GBC is the most common malignancy of the biliary tract. As majority of patient present with locally advanced disease a potential curative resection warrants an aggressive surgical approach, which includes liver resection, lymph node clearance and resection of involved adjacent organs. Although this is a formidable surgery, it is the only chance for long-term survival.

 

BJHS 2018;3(2)6:427-431.

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Author Biographies

Sushil Bahadur Rawal, Nepalese Army Institute of Health Sciences
Associate Professor, Department of Surgery
Kunda Bikram Shah, Nepalese Army Institute of Health Sciences
Assistant Professor, Department of Surgery
Dhana Bahadur Shrestha, Nepalese Army Institute of Health Sciences
Medical Officer
Srijan Malla, Nepalese Army Institute of Health Sciences
Associate Professor, Department of Surgery
Jyoti Rayamajhi, Nepalese Army Institute of Health Sciences
Associate Professor, Department of Surgery
Manoj Kumar Jha, Nepalese Army Institute of Health Sciences
Assistant Professor, Department of Surgery
Anup Thapa, Nepalese Army Institute of Health Sciences
Assistant Professor, Department of Surgery
Published
2018-09-05
How to Cite
Rawal, S., Shah, K., Shrestha, D., Malla, S., Rayamajhi, J., Jha, M., & Thapa, A. (2018). Gall bladder cancer: A single center experience. Birat Journal of Health Sciences, 3(2), 427-431. https://doi.org/10.3126/bjhs.v3i2.20939
Section
Original Research Articles