Relation between ABO blood group and Helicobacter pylori infection among patients with peptic ulcer disease at Provincial Hospital: A cross sectional study

Authors

  • Mahesh Mahaseth Provincial hospital, Province-2, Janakpur, Nepal
  • Gaurang Mishra Provincial hospital, Province-2, Janakpur, Nepal
  • Sanjeet Jha Provincial hospital, Province-2, Janakpur, Nepal
  • Manish Pandey Provincial hospital, Province-2, Janakpur, Nepal
  • Gyanendra Yadav Provincial hospital, Province-2, Janakpur, Nepal
  • Gautam Sah Provincial hospital, Province-2, Janakpur, Nepal

DOI:

https://doi.org/10.3126/mjmms.v1i1.42958

Keywords:

ABO blood groups, H. pylori, peptic ulcer disease

Abstract

INTRODUCTION: To document the potential relationship between Helicobacter pylori infection (H. pylori), ABO and Rhesus (Rh) blood groups in affected individuals with peptic ulcer disorder.

MATERIALS AND METHODS: This cross-sectional, research was accomplished from February 2021 to May 2021 among individuals experiencing dyspeptic conditions visiting Endoscopy Unit of Janakpur Provincial Hospital. All the patients were investigated for their blood group phenotype and Rhesus dependent through slide hemagglutination test. Also all the patients went through esophagogastroduodenoscopy (EGD) in order to identify peptic ulcer disease. Gastric biopsies were acquired and evaluated for H. pylori through urease test.

RESULTS: A total of 103 patients were registered in this study, which included 49 males and 54 females with a mean age of 15-77 years. H. pylori was found positive in 75(72.8%) cases and negative in 28 (27.2%) cases, Blood group A, B, AB and O were found in 19.4%, 33.0%, 13.6%, and 34.0% of the patients respectively. Relatively higher prevalence of H. pylori was found in each blood groups O (33.3%) and B (33.3%) compared to blood group A (20.1%) and AB (13.3%). However, association of ABO blood group and prevalence of H. pylori was found to be insignificant (p=0.991).

CONCLUSIONS: The study concluded that B blood group people were more prone to H. pylori infection. Our study revealed that H. pylori contamination was definitely an endemic issue, which needs to be handled by enhancing hygiene, supply of filtered water and in addition other measures for its elimination. Further meticulous studies are needed to establish relationship between blood type and H. pylori contamination in different age groups.

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Author Biographies

Mahesh Mahaseth, Provincial hospital, Province-2, Janakpur, Nepal

Department of Medicine

Gaurang Mishra, Provincial hospital, Province-2, Janakpur, Nepal

Department of Medicine

Sanjeet Jha, Provincial hospital, Province-2, Janakpur, Nepal

Department of Medicine

Manish Pandey, Provincial hospital, Province-2, Janakpur, Nepal

Department of Medicine

Gyanendra Yadav, Provincial hospital, Province-2, Janakpur, Nepal

Department of Medicine

Gautam Sah, Provincial hospital, Province-2, Janakpur, Nepal

Department of Medicine

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Published

2021-12-31

How to Cite

Mahaseth, M., Mishra, G., Jha, S., Pandey, M., Yadav, G., & Sah, G. (2021). Relation between ABO blood group and Helicobacter pylori infection among patients with peptic ulcer disease at Provincial Hospital: A cross sectional study. MedS Alliance Journal of Medicine and Medical Sciences, 1(1), 95–100. https://doi.org/10.3126/mjmms.v1i1.42958

Issue

Section

Original Investigations