Profile of Skin Biopsies and Patterns of Granulomatous Skin Diseases in a Tertiary Care Center of Western Nepal

Authors

  • Ajay Kumar Manipal College of Medical Sciences, Pokhara, Nepal
  • Saujan Subedi Gandaki Medical College, Pokhara Nepal
  • Jenny Pun Manipal College of Medical Sciences, Pokhara, Nepal
  • Binamra Basnet Manipal College of Medical Sciences, Pokhara, Nepal
  • Raja Babu Giri Manipal College of Medical Sciences, Pokhara, Nepal
  • Mohammad Asim Hamad General Hospital, Doha, Qatar
  • Brijesh Sathian Rumailah Hospital, Hamad Medical Corporation, Doha, Qatar

DOI:

https://doi.org/10.3126/mjpahs.v3i2.35614

Keywords:

Granuloma, hitopathology, leprosy, skin biopsy

Abstract

Background: Granulomatous skin diseases are one of the leading causes of morbidity in tropical countries like Nepal. These granulomatous skin lesions often pose diagnostic challenge to clinicians as well as to dermatopathologists. Histopathologic examination of a biopsy specimen represents one of the most informative and cost-effective procedure and may help to avoid other, costlier and invasive diagnostic workup.

Materials and Methods: This cross-sectional observational study from October 2018 to October 2019, at department of dermatology, enrolled 142 cases of skin biopsies. Correlation between clinical impression and histopathological findings was evaluated.

Results: Out of 13940 dermatology visits/ consultations, 142 (1.01%) skin biopsies were performed. Head, neck and face were the commonest sites of biopsies (29.6%). The most common biopsy technique was incisional type in 70 (50.4%). Histopathology showed granulomatous features in 49 (34.8%) cases, out of which tuberculoid type was the commonest, in 29 (58.0%). Positive clinicopathological correlation was seen in 117/142 (82.4%) for all biopsies and 41/49 (85%) for granulomaous skin lesions.

Conclusion: Tuberculoid type was the most common cutaneous granuloma. High clinicopathological correlation in our study supports histopathology as an important tool for diagnosis of granulomatous as well overall skin disorders.

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Author Biographies

Ajay Kumar, Manipal College of Medical Sciences, Pokhara, Nepal

Department of Dermatology

Saujan Subedi, Gandaki Medical College, Pokhara Nepal

Department of Dermatology

Jenny Pun, Manipal College of Medical Sciences, Pokhara, Nepal

Department of Dermatology

Binamra Basnet, Manipal College of Medical Sciences, Pokhara, Nepal

Department of Dermatology

Mohammad Asim, Hamad General Hospital, Doha, Qatar

Department of Surgery

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Published

2020-12-31

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Section

Articles