Utility of Neutrophil to Lymphocyte ratio and platelet to lymphocyte ratio as early predicter of severe acute biliary pancreatitis

Authors

  • Surendra Shah Patan Academy of Health Sciences, Lagankhel, Nepal https://orcid.org/0000-0002-0510-3952
  • Sanjaya Paudyal Patan Academy of Health Sciences, Lagankhel, Nepal
  • Shanta Bir Maharjan Patan Academy of Health Sciences, Lagankhel, Nepal
  • Shailendra Shah Patan Academy of Health Sciences, Lagankhel, Nepal
  • Jay Narayan Shah Patan Academy of Health Sciences, Lagankhel, Nepal

DOI:

https://doi.org/10.3126/nmj.v4i1.37094

Keywords:

Acute biliary pancreatitis; Organ failure; Neutrophil to lymphocyte ratio; Platelet to lymphocyte ratio

Abstract

Introduction: Acute severe pancreatitis is associated with increased mortality. Several scoring systems have been used to predict severe acute pancreatitis which are either time-consuming or calculated 48 hours after admission. This study was aimed to assess the utility of neutrophils to lymphocyte ratio and platelet to lymphocyte ratio as an early predictor of severe acute biliary pancreatitis.
Materials and Methods: This was a retrospective cohort study conducted from January 2017 to January 2020. Patients with non-biliary pancreatitis, referred after initial treatment, missed data, and acute pancreatitis with acute cholecystitis or cholangitis were excluded from the study. Data were collected from case sheets. Patients were divided into two groups according to the development of severe acute biliary pancreatitis based on the revised Atlanta Classification. Association of neutrophil to lymphocyte ratio and platelet to lymphocyte ratio with severe acute biliary pancreatitis was assessed using Mann Whitney U-test. p-value < 0.05 was considered as statistically significant.
Results: Total 73 cases included in the study (males/females= 0.55). Sixty-six patients (90.4%) had mild/moderate acute biliary pancreatitis, and 7 (9.6%) patients had severe acute biliary pancreatitis. There was a development of complications in 7 (9.6%) patients who had severe acute biliary pancreatitis including one mortality. The mean neutrophil to lymphocyte ratio and mean platelet to lymphocyte ratio were high in the severe acute biliary pancreatitis group compared to the nonsevere acute biliary pancreatitis group, however, these differences were not statistically significant.
Conclusions:  Neutrophil to lymphocyte ratio and platelet to lymphocyte ratio cannot predict severe acute biliary pancreatitis.

Downloads

Download data is not yet available.
Abstract
60
PDF
34

Author Biographies

Surendra Shah, Patan Academy of Health Sciences, Lagankhel, Nepal

Department of Surgery

Sanjaya Paudyal, Patan Academy of Health Sciences, Lagankhel, Nepal

Department of Surgery

Shanta Bir Maharjan, Patan Academy of Health Sciences, Lagankhel, Nepal

Department of Surgery

Shailendra Shah, Patan Academy of Health Sciences, Lagankhel, Nepal

Department of Surgery

Jay Narayan Shah, Patan Academy of Health Sciences, Lagankhel, Nepal

Department of Surgery

Downloads

Published

2021-06-30

How to Cite

Shah, S., Paudyal, S., Maharjan, S. B., Shah, S., & Shah, J. N. (2021). Utility of Neutrophil to Lymphocyte ratio and platelet to lymphocyte ratio as early predicter of severe acute biliary pancreatitis. Nepalese Medical Journal, 4(1), 410–413. https://doi.org/10.3126/nmj.v4i1.37094

Issue

Section

Original Articles