Bacteriological Profile of Burn Patients and Antimicrobial Susceptibility Pattern of their Wound Isolates at Nepal Cleft and Burn Center

  • Apar Lamichhane National Academy of Medical Sciences (NAMS), Kathmandu, Nepal
  • Kiran Kishor Nakarmi Kirtipur Hospital, Kirtipur, Nepal
  • Peeyush Dahal National Academy of Medical Sciences (NAMS), Kathmandu, Nepal
  • Surendra Jung Basnet Kirtipur Hospital, Kirtipur, Nepal
  • Pashupati Babu Pokharel National Academy of Medical Sciences (NAMS), Kathmandu, Nepal
  • Suraj Bhattarai Global Institute for Interdisciplinary Studies, Kathmandu, Nepal
  • Shankar Man Rai Global Institute for Interdisciplinary Studies, Kathmandu, Nepal
Keywords: Antimicrobial susceptibility, burn infection, bacteriological profile

Abstract

Background: Burn infections are the major causes of morbidity and mortality in burn patients. The infectious agent could be both Gram positive and Gram negative bacteria. The aim of this research was to study the bacteriological profile of burn patients and anti-microbial susceptibility pattern of their wound isolates.

 Methods: This cross-sectional study was conducted in Kirtipur Hospital, Nepal from January 1st to March 31st 2019. A total of 109 burn patients were included and their wound swabs were collected at the time of admission. All isolates were identified by standardized microbiological procedures. Anti-microbial susceptibility tests were performed by Kirby Bauer disc diffusion method.

Results: Of 109 burn wound samples, 56 (59%) yielded culture growth and the Gram negative isolates were more common than Gram positives (77% vs. 23%). The most common organism isolated was Klebsiella spp. (25%) followed by Acinetobacter spp. (21%) and Staphylococcus aureus (18%). Most burn wound isolates were of resistant strain. Particularly, highly resistant strain of Acinetobacter spp. were isolated, most of which were sensitive to Tigecycline, Polymyxin B and Colistin only.

Conclusion : Gram negative isolates were common in burn wound isolates and the antibiotic susceptibility pattern was different for different organisms. The use of antimicrobials should be judicious to further not escalate the problem of antimicrobial resistance in the healthcare settings.

 

Downloads

Download data is not yet available.
Abstract
69
PDF
25

Author Biographies

Apar Lamichhane, National Academy of Medical Sciences (NAMS), Kathmandu, Nepal

Department of Burns and Plastic Surgery

Kiran Kishor Nakarmi, Kirtipur Hospital, Kirtipur, Nepal

Department of Burns, Plastic and Reconstructive Surgery

Peeyush Dahal, National Academy of Medical Sciences (NAMS), Kathmandu, Nepal

HOD Department of Burns and Plastics

Surendra Jung Basnet, Kirtipur Hospital, Kirtipur, Nepal

Consultant Department of Burns, Plastics and Reconstructive Surgery

Pashupati Babu Pokharel, National Academy of Medical Sciences (NAMS), Kathmandu, Nepal

Department of Burns and Plastic Surgery

Published
2019-10-01
How to Cite
Lamichhane, A., Nakarmi, K., Dahal, P., Basnet, S., Pokharel, P., Bhattarai, S., & Rai, S. (2019). Bacteriological Profile of Burn Patients and Antimicrobial Susceptibility Pattern of their Wound Isolates at Nepal Cleft and Burn Center. Journal of College of Medical Sciences-Nepal, 15(3), 160-166. https://doi.org/10.3126/jcmsn.v15i3.24363
Section
Original Articles