Treatment Non-Compliance in Patients with Schizophrenia

  • Sandip Subedi Department of Psychiatry, Universal College of Medical Sciences, Bhairahawa, Nepal
  • Kamala Paudel Psychiatry Nursing, Manmohan Memorial Institute of Health Sciences, Kathmandu
  • Dev Kumar Thapa Department of Psychiatry, Gandaki Medical College, Pokhara
Keywords: Schizophrenia, compliance, non-compliance, factors affecting compliance

Abstract

INTRODUCTION: Non-compliance to medication in Schizophrenia is a common problem.  It leads to frequent recurrence of Psychosis which has negative impact on individuals and their families. Understanding and reducing non-adherence is therefore a key challenge to quality care for patients with Schizophrenia. This study was conducted with the aim of determining the incidence and factors associated with medication non-compliance among patients suffering from schizophrenia.

MATERIAL AND METHODS: This cross-sectional study included 94 schizophrenic subjects who visited psychiatric OPD of tertiary level hospital. Disproportionate stratified random sampling method was applied to collect the data. Socio-demographic data sheet, data sheet to collect the various factors of compliance and the 8-item Morisky Medication Adherence Scale (MMAS-8) were used for data collection by interview method. 

RESULTS: The prevalence of non-compliance was 89.4%. With regards to association between noncompliance and demographic characteristics, there was high non-compliance rate in age below 40 years (54.2%), male (52.1%), married (64.8%) and low economic status (52%). Medication non-compliance were high in patients with medication side effects dizziness (60.6%), sedation (66%), longer duration of illness (92.8%) & having 1-3 pills (47.8%).

CONCLUSION: Medication Non-Compliance in Schizophrenia was high. Measures that can increase compliance like psycho-educational programmes on compliance and the active involvement of the relatives and significant others in the management of patients of mentally ill patients are recommended.

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Published
2020-06-30
How to Cite
Subedi, S., Paudel, K., & Thapa, D. (2020). Treatment Non-Compliance in Patients with Schizophrenia. Journal of Universal College of Medical Sciences, 8(1), 3-8. https://doi.org/10.3126/jucms.v8i1.29773
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Original Articles