Maternal and perinatal outcome in patients with severe pre eclampsia/ eclampsia with and without HELLP syndrome

Authors

  • T Gupta Associate Professor, Department of Obstetrics and Gynaecology, ESI Postgraduate Institute of Medical Sciences & Research, Delhi
  • N Gupta Assistant Professor, Department of Obstetrics and Gynaecology, ESI Postgraduate Institute of Medical Sciences & Research, Delhi
  • J Jain Post Graduate Resident, Department of Obstetrics and Gynaecology, ESI Postgraduate Institute of Medical Sciences & Research, Delhi
  • S Gupta Assistant Professor, Department of Obstetrics and Gynaecology, ESI Postgraduate Institute of Medical Sciences & Research, Delhi
  • P Bhatia Professor, Department of Obstetrics and Gynaecology, ESI Postgraduate Institute of Medical Sciences & Research, Delhi
  • J Bagla Associate Professor, Department of Paediatrics, ESI Postgraduate Institute of Medical Sciences & Research, Delhi

DOI:

https://doi.org/10.3126/jucms.v1i4.9564

Keywords:

HELLP syndrome, Severe pre eclampsia, Maternal mortality

Abstract

OBJECTIVE: To evaluate the occurrence of HELLP syndrome inpatients with severe pre eclampsia & eclampsia and to compare the maternal & perinatal outcome in patients with and without HELLP syndrome (partial and true).

METHOD: This was a prospective longitudinal study conducted in the Department of Obstetrics & Gynaecology, E.S.I. PGIMSR,NewDelhi from August 2011-April 2013. 50 pregnant women with singleton pregnancy with severe pre eclampsia detected at 28 or more weeks of gestation were enrolled. Patients were divided into three groups: group 1 with severe pre eclampsia, group 2 with severe pre eclampsia with partial HELLP syndrome and group 3 with severe pre eclampsia with true HELLP syndrome. Patients in three groups were compared in regard to maternal complications, gestational age atdelivery, mode ofdelivery, hospital stay andperinatal outcome.

RESULTS: Prevalence of HELLP syndrome in severe pre eclampsia was 40% (partial HELLP= 28% and true= 12%). Antenatal and maternal complications were more in true HELLP syndrome patients as compared to other groups. PPH was observed in 40% of entire study group. DIC was found more in true HELLP syndrome patient with high statistically significant p value<0.001 Blood and its product transfusion was more in true HELLP syndrome. There was 100% ICU admission in group 3. In severe pre eclampsia, 11 neonates had birth weight >2.5kg. Where as in partial and true HELLP syndrome, no neonate had birth weight more than 2.5kg.This difference was statistically significant. There was 100% NICU admission in HELLP syndrome, 91.66% in partial HELLP syndrome and 42.3% in severe preeclampsia. The perinatal morbidity and mortality was higher in HELLP syndrome patients than in patient with severe pre eclampsia without HELLP syndrome.

CONCLUSION: The study concludes that both maternal and perinatal outcome were adverse in HELLP syndrome than in severe pre eclampsia without HELLP syndrome.

DOI: http://dx.doi.org/10.3126/jucms.v1i4.9564

Journal of Universal College of Medical Sciences (2013) Vol.1 No.04: 7-12

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Published

2014-01-12

How to Cite

Gupta, T., Gupta, N., Jain, J., Gupta, S., Bhatia, P., & Bagla, J. (2014). Maternal and perinatal outcome in patients with severe pre eclampsia/ eclampsia with and without HELLP syndrome. Journal of Universal College of Medical Sciences, 1(4), 7–12. https://doi.org/10.3126/jucms.v1i4.9564

Issue

Vol. 1 No. 4 (2013)

Section

Original Articles

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