A contemporary insight of metabolomics approach for COVID-19: Potential for novel therapeutic and diagnostic targets

Authors

DOI:

https://doi.org/10.3126/nje.v10i4.33964

Keywords:

COVID-19, metabolomics, severe disease, diagnosis, therapeutic targets

Abstract

The Coronavirus disease 2019 (COVID-19) pandemic is caused by rapidly spreading pathogenic virus known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), that affects vast majority of population worldwide. Although, around 80% of the cases had mild infection but still remaining 20% had developed respiratory failure and dysfunction of other organs that necessitate urgent oxygen therapy or specific interventions. Therefore, it is imperative to establish novel prognostic approaches to screen patients at high-risk of developing severe complications. The primary focus of current research for COVID-19 is to discover safe and efficacious vaccine for prevention and effective treatment for better management of the patients to overcome the pandemic. To achieve this goal, it is imperative to have better understanding of the molecular pathways involved in the pathophysiology and progression of severe COVID-19.  The surge for reliable diagnostics and therapeutics targets for COVID-19 highlighted the great potential of high-throughput approach like metabolomics which may enable the development of personalized medicine.

 

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Author Biographies

Mohammad Asim, Trauma and vascular surgery, Hamad General Hospital, Doha

Trauma and vascular surgery, Hamad General Hospital, Doha

Brijesh Sathian, Rumailah Hospital, Hamad Medical Corporation

2Scientist, Geriatrics and long term care Department, Doha, Qatar

3Centre for Midwifery, Maternal and Perinatal Health, Bournemouth University, Bournemouth, England, United Kingdom

Indrajit Banerjee, Sir Seewoosagur Ramgoolam Medical College: Belle Rive, Vacoas-Phoenix, MU

Associate Professor, Department of Pharmacology, Sir Seewoosagur Ramgoolam Medical College: Belle Rive, Vacoas-Phoenix, MU

Jared Robinson, Sir Seewoosagur Ramgoolam Medical College: Belle Rive, Vacoas-Phoenix, MU

Sir Seewoosagur Ramgoolam Medical College: Belle Rive, Vacoas-Phoenix, MU

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Published

2020-12-31

How to Cite

Asim, M., Sathian, B., Banerjee, I., & Robinson, J. (2020). A contemporary insight of metabolomics approach for COVID-19: Potential for novel therapeutic and diagnostic targets. Nepal Journal of Epidemiology, 10(4), 923–927. https://doi.org/10.3126/nje.v10i4.33964

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Section

Short Communications