Turner's Syndrome: Approach to Diagnosis and Treatment

  • Sadhana Sah Kathmandu Model Hospital, Kathmandu, Nepal http://orcid.org/0000-0002-3319-5516
  • Ganesh Dangal Kathmandu Model Hospital, Kathmandu, Nepal
  • Aruna Karki Kathmandu Model Hospital, Kathmandu, Nepal
  • Hema Pradhan Kathmandu Model Hospital, Kathmandu, Nepal
  • Ranjana Shrestha Kathmandu Model Hospital, Kathmandu, Nepal
  • Kabin Bhattachan Kathmandu Model Hospital, Kathmandu, Nepal
  • Rekha Poudel Kathmandu Model Hospital, Kathmandu, Nepal
  • Nishma Bajracharya Kathmandu Model Hospital, Kathmandu, Nepal
  • Umesh Jha Kathmandu Model Hospital, Kathmandu, Nepal
  • Kenusha Tiwari Kathmandu Model Hospital, Kathmandu, Nepal
  • Sonu Bharati Kathmandu Model Hospital, Kathmandu, Nepal
Keywords: hypergonadotrophic hypogonadism, primary amenorrhea, Turner's Syndrome

Abstract

Turner's syndrome is the most common karyotypic abnormality causing gonadal failure and primary amenorrhea. It is characterized by short stature and absence of secondary sexual characteristics. It is diagnosed by increased plasma FSH and LH level with low level of estrogen i.e. hypergonadotrophic hypogonadism. Ultrasound abdomen reveals streak ovaries and atrophic uterus. Karyotype confirms the diagnosis of Turner's syndrome (45XO).

We present here a 15 years girl who presented with primary amenorrhea with short stature with breast development corresponds to Tanner stage I. Her FSH was raised. Ultrasound abdomen showed uterine agenesis and streak ovaries. Karyotype showed 45XO which confirmed the diagnosis of Turner's syndrome. She is now on estrogen therapy and her height has increased and breast development corresponds to Tanner stage II.

Keywords: hypergonadotrophic hypogonadism, primary amenorrhea, Turner's syndrome

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Author Biographies

Sadhana Sah, Kathmandu Model Hospital, Kathmandu, Nepal

Department of Obstetrics and Gynaecology

Ganesh Dangal, Kathmandu Model Hospital, Kathmandu, Nepal

Department of Obstetrics and Gynecology

Aruna Karki, Kathmandu Model Hospital, Kathmandu, Nepal

Department of Obstetrics and Gynecology

Hema Pradhan, Kathmandu Model Hospital, Kathmandu, Nepal

Department of Obstetrics and Gynecology

Ranjana Shrestha, Kathmandu Model Hospital, Kathmandu, Nepal

Department of Obstetrics and Gynecology

Kabin Bhattachan, Kathmandu Model Hospital, Kathmandu, Nepal

Department of Obstetrics and Gynecology

Rekha Poudel, Kathmandu Model Hospital, Kathmandu, Nepal

Department of Obstetrics and Gynecology

Nishma Bajracharya, Kathmandu Model Hospital, Kathmandu, Nepal

Department of Obstetrics and Gynecology

Umesh Jha, Kathmandu Model Hospital, Kathmandu, Nepal

Department of Obstetrics and Gynecology

Kenusha Tiwari, Kathmandu Model Hospital, Kathmandu, Nepal

Department of Obstetrics and Gynecology

Sonu Bharati, Kathmandu Model Hospital, Kathmandu, Nepal

Department of Obstetrics and Gynecology

Published
2018-12-31
How to Cite
Sah, S., Dangal, G., Karki, A., Pradhan, H., Shrestha, R., Bhattachan, K., Poudel, R., Bajracharya, N., Jha, U., Tiwari, K., & Bharati, S. (2018). Turner’s Syndrome: Approach to Diagnosis and Treatment. Nepal Journal of Obstetrics and Gynaecology, 13(3), 61-62. https://doi.org/10.3126/njog.v13i3.23476
Section
Case Reports