Isolation, Identification and Antimicrobial Activity of a Withanolide [WS-1] from the Roots of Withania somnifera

Authors

  • Prakash Kharel Central Department of Chemistry, Tribhuvan University, Kathmandu
  • Mangala D Manandhar Nepal Academy of Science and Technology (NAST), Lalitpur
  • Surya K Kalauni Central Department of Chemistry, Tribhuvan University, Kathmandu
  • Suresh Awale Institute of Natural Medicine, University of Toyama, Sugitani, Toyama
  • Janaki Baral Central Department of Chemistry, Tribhuvan University, Kathmandu

DOI:

https://doi.org/10.3126/njst.v12i0.6497

Keywords:

antimicrobial analysis, MIC, Withania, Withanolide, ZOI

Abstract

Column chromatographic purification of the organic extract obtained from the roots of Withania somnifera yielded a biologically active withanolide compound WS-1 whose structure was established on the basis of spectroscopic evidences. Potent antibacterial activity was observed in this compound.

DOI: http://dx.doi.org/10.3126/njst.v12i0.6497

Nepal Journal of Science and Technology 12 (2011) 179-186

 

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Published

2012-07-22

How to Cite

Kharel, P., Manandhar, M. D., Kalauni, S. K., Awale, S., & Baral, J. (2012). Isolation, Identification and Antimicrobial Activity of a Withanolide [WS-1] from the Roots of Withania somnifera. Nepal Journal of Science and Technology, 12, 179–186. https://doi.org/10.3126/njst.v12i0.6497

Issue

Vol. 12 (2011)

Section

Articles

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Authors retain copyright and grant the journal right of first publication.