Antioxidant Property, Cytotoxicity and Antimicrobial Activity of Lasia spinosa Leaves

Authors

  • Durajan Goshwami Department of Pharmacology, National Medical College Teaching Hospital and Research Center, Birgunj, Parsa
  • Md. Mostafizur Rahman Department of Clinical Pharmacy & Pharmacology, Faculty of Pharmacy, University of Dhaka, Dhaka-1000,
  • Md. Abdul Muhit Department of Clinical Pharmacy & Pharmacology, Faculty of Pharmacy, University of Dhaka, Dhaka-1000,
  • Md. Saiful Islam Department of Clinical Pharmacy & Pharmacology, Faculty of Pharmacy, University of Dhaka, Dhaka-1000,
  • Mukhtar Anasri Department of Pharmacology, National Medical College Teaching Hospital and Research Center, Birgunj, Parsa

DOI:

https://doi.org/10.3126/njst.v13i2.7739

Keywords:

antimicrobial, antioxidant, cytotoxic, Lasia spinosa

Abstract

This study was undertaken to evaluate antioxidant property, cytotoxicity and antimicrobial activity of Lasia spinosa leaves. Ethyl acetate soluble partitionate of the methanolic extract of the plant material showed significant antioxidant property using DPPH (1,1-diphenyl-2-pecrylhydrazyl) assay with IC50 value of 16.42 ?g/ml. In the brine shrimp lethality bioassay, LC50 values obtained from the best fit line slope were 0.544, 3.181, and 4.096 ?g/mL for standard (vincristine sulphate), dichloromethane and ethylacetate soluble partitionates of the methanolic extract respectively. The leaves extracts showed mild antimicrobial property.

Nepal Journal of Science and Technology Vol. 13, No. 2 (2012) 215-218

DOI: http://dx.doi.org/10.3126/njst.v13i2.7739

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Published

2013-03-10

How to Cite

Goshwami, D., Rahman, M. M., Muhit, M. A., Islam, M. S., & Anasri, M. (2013). Antioxidant Property, Cytotoxicity and Antimicrobial Activity of Lasia spinosa Leaves. Nepal Journal of Science and Technology, 13(2), 215–218. https://doi.org/10.3126/njst.v13i2.7739

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Articles