Seroprevalence 0f Dengue Virus Infection in Nepal

  • B P Gupta Central Department of Biotechnology, Tribhuwan University, Kirtipur, Kathmandu, Nepal
  • S K Mishra National Public Health laboratory, Teku, Kathmandu, Nepal
  • K D Manandhar Central Department of Biotechnology, Tribhuwan University, Kirtipur, Kathmandu, Nepal
  • R Malla Central Department of Biotechnology, Tribhuwan University, Kirtipur, Kathmandu, Nepal
  • C S Tamarakar Dean, Science and Technology, Tribhuvan University, Kirtipur
  • P P Raut Civil Service Hospital of Nepal , New Baneshwor, Kathmandu
  • S K Sah B. P. Koirala memorial cancer Hospital, Bharatpur, Nepal
  • S Pokhrel Universal College of Medical Sciences, Nepal
  • R Rauniyar Dayananda Sagar Institutions, Bangalore
  • A. Bajaracharya Bir Hospital Trauma Centre, Kathamandu, Nepal
Keywords: Dengue fever, IgM ELISA, Terai region

Abstract

Dengue Virus infection is an emerging mosquito-borne disease. It is a global health problem and its expanding endemicity towards new territories is a serious concern. Relatively a new disease in Nepalese context, dengue abruptly appeared as massive outbreak in 2010, merely four years after its first introduction. It is a nagging public health problem in the low lands of Terai, expanding to new areas of Nepal in recent years.  A cross-sectional study was conducted to determine anti-Dengue IgM positive rate in Lumbini, Dhading and Chitwan district. The study was carried from June 2012 to November 2012. The total number of Serum samples was collected from 275 patients visiting hospitals with history of fever, headache and suspected DF. The samples were examined by ELISA. The anti-Dengue IgM positivity was found to be 29.09 %. The positive rate was highest in Dhading (70.37%) followed by Bharatpur (37.6%) and Lumbini (11.38%). The Dengue positive cases were higher in males (32.5 %) than female (24.8 %). The highest positive cases (41.6%) were from age group less than 15 years. Dengue has substantial expansion in Western and Far Western Terai region of Nepal which was limited to the middle Terai region in the past and mostly infects older people.

DOI: http://dx.doi.org/10.3126/ijasbt.v1i4.9135

 Int J Appl Sci Biotechnol, Vol. 1(4): 224-227

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Abstract
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PDF
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Published
2013-12-21
How to Cite
Gupta, B., Mishra, S., Manandhar, K., Malla, R., Tamarakar, C., Raut, P., Sah, S., Pokhrel, S., Rauniyar, R., & Bajaracharya, A. (2013). Seroprevalence 0f Dengue Virus Infection in Nepal. International Journal of Applied Sciences and Biotechnology, 1(4), 224-227. https://doi.org/10.3126/ijasbt.v1i4.9135
Section
Research Articles